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Masters Thesis | Medicine | Indonesia | Volume 10 Issue 8, August 2021
Level of 25 (OH) Vitamin D Lower in Central Obesity Women Compared to Normal Weight Women and its Correlation with Blood Pressure
Linda Sinto | Wimpie Pangkahila  | Wayan Weta 
Abstract: Obesity is one of the biggest health challenges of this century. Central obesity cause chronic low inflammation. Vitamin D has a role in reducing inflammation. Central obesity people need higher Vitamin D, but Vitamin D utility was found lower in central obesity people. This may because the amount of Vitamin D is trapped in fat. This study was a cross sectional study compare within central obesity and normal weight woman. The sample was taken by consecutive sampling method. The subjects were 16 obese central women and 16 normal weight women. Demographic data, sun exposure and food intake containing vitamin D were obtained from interviews. Than blood pressure checked and blood sampling were taken to check fasting blood sugar levels, HDL, triglycerides, 25(OH) Vitamin D. Results showed that median level of 25 (OH) Vitamin D in the obese women group was lower than in normal weight women 7,84(7,12:10,70) VS 15,20 (10, 42: 19, 47); p=0,003. The median sun exposure in the group of central obese women was lower than women of normal weight 2, 05 (0: 5, 50) VS 17, 50 (6, 25: 25, 50); p=0,001. While food intake containing Vitamin D does not have a significant comparison. The correlation test results between 25(OH) Vitamin D levels and metabolic indicators showed no correlation in the group of normal weight women. Whereas in the group of central obese women, levels of 25 (OH) Vitamin D had a correlation with systolic, diastolic blood pressure and MAP (p=0,001, p=0.006, p=0,003, respectively) but did not have a correlation with fasting blood sugar, HDL and triglycerides. Conclusion of this study is 25 (OH) Vitamin D levels in central obese women group proved to be lower than normal weight women and had a negative correlation with blood pressure in central obese women group.
Keywords: Vitamin D, obesity, metabolic syndrome, inflammation
Edition: Volume 10 Issue 8, August 2021,
Pages: 6 - 8
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