International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 2

Research Paper | Medicine | India | Volume 10 Issue 6, June 2021


A Study of Platelet to Lymphocyte Ratio in Patients with Metabolic Syndrome

Sakshi Jha, Mahesh Kumar Mehrotra


Abstract: Background: The incidence and prevalence of the metabolic syndrome varies all over the world, showcasing the age and ethnicity of the populations taken into account and the diagnostic criteria applied. Various studies have indicated an association of Metabolic Syndrome (MS) and insulin resistance (IR) with inflammation. Platelet-lymphocyte ratio (PLR) has emerged as a novel inflammatory index that may reflect the extent of inflammation and overall mortality. This study aims to evaluate the PLR in patients with MS and to establish its correlation with the severity of MS. Methods: A cross sectional study was conducted on 250 outpatient subjects at SRMS Hospital, Bareilly (125 subjects with Metabolic Syndrome and another 125 age and gender matched control participants without Metabolic Syndrome). Thorough history including history of risk factors if any, physical examinations and basic investigations like complete blood counts, Fasting and Random blood sugars HbA1c levels, fasting lipid profile, ECG were done and the data was analyzed and interpreted using appropriate statistical methods. Results: PLR when compared was 6.9% higher in male?s subjects as compared to female?s subjects with metabolic syndrome. PLR was 95.9% higher in subjects with metabolic syndrome as compared to subjects without metabolic syndrome (p<0.05). Also, there was a rise in PLR in male subjects as severity of metabolic syndrome increased. Conclusions: In this study, PLR beyond 90 ruled in favour of significant inflammation. PLR is calculated from complete blood count along with differential leucocyte count. It is an affordable, easily and widely available marker of inflammation, which can help in the risk stratification of patients with various cardiovascular diseases along with the traditionally used markers.


Keywords: Insulin resistance, Metabolic syndrome


Edition: Volume 10 Issue 6, June 2021,


Pages: 132 - 134


How to Cite this Article?

Sakshi Jha, Mahesh Kumar Mehrotra, "A Study of Platelet to Lymphocyte Ratio in Patients with Metabolic Syndrome", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SR21530150849, Volume 10 Issue 6, June 2021, 132 - 134

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Insulin resistance'

Downloads: 55

Research Paper, Medicine, Egypt, Volume 10 Issue 2, February 2021

Pages: 1653 - 1658

Non Alcoholic Fatty Pancreatic Disease Significance, Importance and Risk factors

Abdelkader Ahmed Abdelkader, Magdy Abd-Alkareem Al-Dahshan, Mohammed Salah Ali, Mohammed Othman Othman, Yosry Zaki Al-Zohairy

Share this Article

Downloads: 139

Research Paper, Medicine, India, Volume 9 Issue 1, January 2020

Pages: 1380 - 1382

Plasma Uric Acid Level and its Association with Type II Diabetes Mellitus

Dr. Manjiri R. Naik, Dr. Nishant R. Agrawal, Dr. Indu Dasari

Share this Article

Similar Articles with Keyword 'Metabolic syndrome'

Downloads: 1

Research Paper, Medicine, India, Volume 10 Issue 10, October 2021

Pages: 1237 - 1240

Prevalence of Anemia in Patients with COPD and its Impact on Quality of Life

Abhishek Verma, Rajiv Garg, Surya Kant

Share this Article

Downloads: 5 | Monthly Hits: ⮙1

Masters Thesis, Medicine, Indonesia, Volume 10 Issue 8, August 2021

Pages: 6 - 8

Level of 25 (OH) Vitamin D Lower in Central Obesity Women Compared to Normal Weight Women and its Correlation with Blood Pressure

Linda Sinto, Wimpie Pangkahila, Wayan Weta

Share this Article

Similar Articles with Keyword 'Insulin'

Downloads: 1 | Monthly Hits: ⮙1

Case Studies, Medicine, India, Volume 10 Issue 11, November 2021

Pages: 467 - 468

Nonketotic Hyperglycemic Hemichorea in a Patient with Uncontrolled Diabetes: A Case Report

Dr. Nirav Goswami, Dr. Leena Dabhi

Share this Article

Downloads: 2

Review Papers, Medicine, Saudi Arabia, Volume 10 Issue 4, April 2021

Pages: 1042 - 1045

Impact of Gestational Diabetes Mellitus (GDM) on the Platelet Activity and Coagulation System

Dr Osama M Alshehri

Share this Article

Similar Articles with Keyword 'resistance'

Downloads: 0

Research Paper, Medicine, India, Volume 10 Issue 12, December 2021

Pages: 807 - 811

MRI Study for Comparative Measurement of Cardiac Parameters between Endurance and Resistance Athletes

Sandip Maheshwari

Share this Article

Downloads: 24 | Monthly Hits: ⮙1

Research Paper, Medicine, Indonesia, Volume 10 Issue 3, March 2021

Pages: 925 - 929

Antibiotic-Resistant Neisseria gonorrhoeae: A Growing Threat of Multidrug Resistance

Ni Gusti Putu Raka Ariani, Paulus Mario Christopher, Alfred Setyono

Share this Article

Similar Articles with Keyword 'Metabolic'

Downloads: 0

Research Paper, Medicine, Uzbekistan, Volume 9 Issue 11, November 2020

Pages: 1692 - 1696

Comparative Characteristic of Population Mechanisms for Formation of Iron Deficiency States among the Drugging Population

Mamasaliev Ne'matjon Solievich, Usmonov Burkhonjon Umarovich, Kurbanova R. R.

Share this Article

Downloads: 1

Review Papers, Medicine, Indonesia, Volume 10 Issue 9, September 2021

Pages: 1657 - 1661

Polycystic Ovarian Syndrome (PCOS) in Adolescents: A Literature Review

Anak Agung Ngurah Anantasika, I Nyoman Bayu Mahendra, I Wayan Artana Putra, Kadek Ary Widayana

Share this Article

Similar Articles with Keyword 'syndrome'

Downloads: 112

Review Papers, Medicine, Indonesia, Volume 9 Issue 10, October 2020

Pages: 170 - 173

Continuous Abdominal Paracentesis for Successful Management of Severe Ovarian Hyperstimulation Syndrome

Kadek Agus Wijaya, IB Putra Adnyana

Share this Article

Downloads: 84

Research Paper, Medicine, India, Volume 3 Issue 8, August 2014

Pages: 1694 - 1702

Increased Prevalence of Neuroleptic Malignant Syndrome, Dementia and Fragmented Germ cells with Reduced Endogenous Estrogen

Dr. Elizabeth JeyaVardhini Samuel, Dr. Sanjoy Joseph George

Share this Article
Top