Downloads: 2 | Views: 14
Case Studies | Medical Science | Indonesia | Volume 10 Issue 5, May 2021
Non-Genomic Pathway Corticosteroid in HIV Patient with Pneumocystis Pneumonia - A Case Report
Benny Tjan  | Hamong Suharsono 
Abstract: Steroid hormones are known to mediate physiological cell functions. Corticosteroid are known to have genomic and non-genomic mechanism. Non-genomic mechanism occurs faster than genomic pathway and referred to as extranuclear mechanism. This non-genomic mechanism exerts rapid inhibitory effects on human neutrophil degranulation at the cellular level. We present a 23-year-old patient with HIV and Pneumocystis pneumonia admitted at Wangaya Regional Hospital Denpasar who treated by high dose methylprednisolone to control the inflammation. High dose corticosteroid showed a non-genomic effect in this patient. Non-genomic effect has fast action to control inflammation. We have to control the inflammatory agent properly to achieve an optimal healing of patient. However, the use of high doses corticosteroids should carefully determine to avoid its side effects.
Keywords: Non-genomic corticosteroid, High-dose corticosteroid, HIV, Pneumocystis pneumonia
Edition: Volume 10 Issue 5, May 2021,
Pages: 1046 - 1048
Similar Articles with Keyword 'HIV'
Research Paper, Medical Science, Albania, Volume 11 Issue 11, November 2022Pages: 62 - 64
Risk Factors for Neurocognitive Impairment in HIV-Infected Patients
Dr. Sadik Aliko | Arjan Harxhi 
Research Paper, Medical Science, India, Volume 11 Issue 11, November 2022Pages: 970 - 972
A Study on Incidence of HIV Infection among Pregnant Women Attending Antenatal Clinic in a Tertiary Care Hospital
Guruprasad Shivashimpi | Ruchita Vajpai | Bhavani Patil | Aditya Bondar