International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 2

Case Studies | Medical Science | Indonesia | Volume 10 Issue 5, May 2021


Non-Genomic Pathway Corticosteroid in HIV Patient with Pneumocystis Pneumonia - A Case Report

Benny Tjan, Hamong Suharsono


Abstract: Steroid hormones are known to mediate physiological cell functions. Corticosteroid are known to have genomic and non-genomic mechanism. Non-genomic mechanism occurs faster than genomic pathway and referred to as extranuclear mechanism. This non-genomic mechanism exerts rapid inhibitory effects on human neutrophil degranulation at the cellular level. We present a 23-year-old patient with HIV and Pneumocystis pneumonia admitted at Wangaya Regional Hospital Denpasar who treated by high dose methylprednisolone to control the inflammation. High dose corticosteroid showed a non-genomic effect in this patient. Non-genomic effect has fast action to control inflammation. We have to control the inflammatory agent properly to achieve an optimal healing of patient. However, the use of high doses corticosteroids should carefully determine to avoid its side effects.


Keywords: Non-genomic corticosteroid, High-dose corticosteroid, HIV, Pneumocystis pneumonia


Edition: Volume 10 Issue 5, May 2021,


Pages: 1046 - 1048


How to Cite this Article?

Benny Tjan, Hamong Suharsono, "Non-Genomic Pathway Corticosteroid in HIV Patient with Pneumocystis Pneumonia - A Case Report", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SR21522211419, Volume 10 Issue 5, May 2021, 1046 - 1048

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'HIV'

Downloads: 32

Research Paper, Medical Science, Indonesia, Volume 10 Issue 2, February 2021

Pages: 1009 - 1013

Effect of Art Increasing Hemoglobin in Human Immunodeficiency Virus-Infected Patient with Anemia at Wangaya Hospital in 2018-2020

I Made Bayu Surya Dana, Lisa Anggriani Susanto, Ketut Suryana

Share this Article

Downloads: 42

Research Paper, Medical Science, Indonesia, Volume 10 Issue 2, February 2021

Pages: 1006 - 1008

Central Nervous System Effect of Efavirenz at Wangaya Hospital 2017 - 2020

Lisa Anggriani Susanto, I Made Bayu Surya Dana, Ketut Suryana

Share this Article

Similar Articles with Keyword 'corticosteroid'

Downloads: 1 | Monthly Hits: ⮙1

Research Paper, Medical Science, India, Volume 10 Issue 5, May 2021

Pages: 1052 - 1055

RITUXIMAB in Lupus Related Autoimmune Haemolytic Anemia

Mohnish Patel, Prashant Chotalia, Puja Srivastava, Sapan C Pandya

Share this Article

Downloads: 1

Review Papers, Medical Science, Indonesia, Volume 10 Issue 9, September 2021

Pages: 384 - 389

Diffuse Alveolar Hemorrhage: A Medical Emergency with High Mortality

Adelia Ghosali

Share this Article
Top