International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064


Downloads: 4

Research Paper | Cardiology Science | India | Volume 10 Issue 5, May 2021


Hypolipaedemic Activity of Ciraka CuraNam against Atherogenic Diet Induced Hyperlipaedemia in Wistar Albino Rats

Sujeethasai K [2] | Manoharan A [2] | Madhavan S


Abstract: Background: Hypercholesterolemia is a common in global clinical challenge. The high blood cholesterol level has more in coronary heart disease, peripheral vascular disease, diabetes related metabolic syndrome, stroke and hypertension. Hypolipaedemic activity of herbs may contribute to prevent and control of the disease. Aim: To evaluate the hypolipaedemic activity of hydroalcoholic extract of Ciraka curanam against atherogenic diet induced hyperlipaedemia in wistar albino rats. Study design: Observational in-vivo study. Place and duration of study: Animal bred house, Dept. of Pharmacology, Arulmigu Kalasalingam College of Pharmacy, Krishnankoil, Srivilliputtur, Tamilnadu. Materials and methods: Adult male wistar albino rats considering weigh of 150-200gm and atherogenic diet induced animal were selected, and albino rats divided into five groups. After the completion of experimental study, the blood was taken from the rats under mild anesthetic state by retro orbital sinus puncture. The lipid extract was taken for the estimation of lipid parameters. The serum and liver were evaluated for serum total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL) by standard enzymatic calorimetric methods. The data were statistically analyzed by one-way ANOVA followed by Dennett's t-test, and significant Pvalue was considered as < 0.05. Results: Ciraka curanam has significantly reduced in hyperlipidemia state.


Keywords: Hypertension, Hypolipaedemic activity, Ciraka curanam, Atherogenic diet, Wistar albino rats


Edition: Volume 10 Issue 5, May 2021,


Pages: 72 - 75


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Sujeethasai K, Manoharan A, Madhavan S, "Hypolipaedemic Activity of Ciraka CuraNam against Atherogenic Diet Induced Hyperlipaedemia in Wistar Albino Rats", International Journal of Science and Research (IJSR), Volume 10 Issue 5, May 2021, pp. 72-75, https://www.ijsr.net/get_abstract.php?paper_id=SR21501113614

Similar Articles with Keyword 'Hypertension'

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Cardiology Science, India, Volume 11 Issue 12, December 2022

Pages: 1031 - 1035

Prevalence of Pulmonary Hypertension in Children with Sickle Cell Disease

Sandeep P Chaurasia [2] | Ajay K Keshwani | Rohit Salame | Tejus Madavi

Share this Article

Downloads: 3

Research Paper, Cardiology Science, India, Volume 10 Issue 12, December 2021

Pages: 970 - 978

A Study on Prescription Analysis and Risk Factors Associated among Cardiovascular Diseased Patients in Tertiary Care Teaching Hospital

Dr. Anusha Joel A | Aishwarya E. Mammen | M. Rani | Yadav Ashish

Share this Article
Top