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Research Paper | Chemistry | India | Volume 10 Issue 4, April 2021
An Efficient Synthesis for Novel 2, 3-Disubstituted -4-Thiazolidones and Antimicrobial Evaluation
Kishor Huge | Vasant Gurav
Abstract: Novel 2-Methyl (2?-hydroxy-3?/5?-chloro-5?/3?-chloromethyl phenyl)- 3- ( 3?/4?-sustitutedphenyl)-4-thiazolidones are synthesized from 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone in good yield with purity. The structure of these compounds are confirmed by IR, 1H NMR and Mass spectra of a representative member from the series. These novel derivatives are then screened for antibacterial and antifungal activities against S. aureus, E. coli, X. citri, E. carotovora, C. albicans, T. rubrum, A. solani and H. turcicum.
Keywords: 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone, 2, 3-Disubstituted-4-thiazolidones, Antibacterial, Antifungal
Edition: Volume 10 Issue 4, April 2021,
Pages: 905 - 908
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