International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Open Access | Double Blind Reviewed

ISSN: 2319-7064


Downloads: 0

Research Paper | Medicine | Indonesia | Volume 10 Issue 12, December 2021


Differences in Initial Lactate Levels on Elderly and Non-Elderly Sepsis Patients Associated With Sofa Score as a Predictor of Mortality in ICU RSUP H. Adam Malik

Febrina Sulaiman | Achsanuddin Hanafie | Adi Koesoema Aman [3]


Abstract: Background: Sepsis, a complex syndrome, multifactorial, incidence, morbidity, mortality are increasing. Old age is a predisposing factor due to co-existing comorbidities, repeated hospitalizations, decreased immunity, functional limitations. Hyperlactanemia is a strong independent predictor of death in sepsis. Objective: Know the differences in initial lactate on elderly and non-elderly patients with sepsis associated with the SOFA score as a predictor of mortality. Method: Using a prospective cohort.30 subjects with sepsis who had measured the initial SOFA score, lactate level were taken as samples. The data then analyzed statistically. Results: The difference between the initial lactate of the elderly ? non-elderly was p = 0.724. The difference in the SOFA score was p = 0.089. The difference in initial lactate in dead patients was p = 0.478. The difference in initial lactate in alive was p = 0.226. Significant difference in the initial lactate in elderly patients who died-alive (p = 0.031). Initial lactate was able to predict mortality in elderly patients (p = 0.013). AUC 93.2% (95% CI = 80.2%-100%). Cut-off point (CoP) was 2.1 mmol / L. The initial lactate sensitivity was 81.8%, specificity was 75% in the elderly. Discussion: Women are more than men with severe sepsis had a higher risk of dying in hospital. In elderly, initial lactate of life and death patients, significant differences were found. Conclusion: Initial lactate predicts mortality in the elderly, cut-off point of 2.1 mmol, elderly patients are admitted to the ICU.


Keywords: Baseline lactate level, Sepsis, Age, SOFA score


Edition: Volume 10 Issue 12, December 2021,


Pages: 1333 - 1336


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Febrina Sulaiman, Achsanuddin Hanafie, Adi Koesoema Aman, "Differences in Initial Lactate Levels on Elderly and Non-Elderly Sepsis Patients Associated With Sofa Score as a Predictor of Mortality in ICU RSUP H. Adam Malik", International Journal of Science and Research (IJSR), Volume 10 Issue 12, December 2021, pp. 1333-1336, https://www.ijsr.net/get_abstract.php?paper_id=SR211222091927

Similar Articles with Keyword 'Sepsis'

Downloads: 0

Case Studies, Medicine, Tanzania, Volume 11 Issue 8, August 2022

Pages: 442 - 444

Subcutaneous Fat Necrosis in a Newborn

Mtagi Kibatala | Asmaa Thena | Mikaly Msangi | Nancy Mugabisho | Gilbert Kwesi

Share this Article

Downloads: 0

Review Papers, Medicine, Albania, Volume 11 Issue 10, October 2022

Pages: 238 - 244

Etiology of Neonatal Encephalopathy: Systematic Review

Ada S??meoni

Share this Article
Top