Research Paper | Medicine | India | Volume 9 Issue 9, September 2020
Diagnostic Role of Lactate Dehydrogenase and Bilirubin Level in Megaloblastic Anemia
Dr. Shyam Bihari Meena | Dr. Vipul Phogat | Dr. Shyoji Ram Meena
Abstract: Objective: To study the change in LDH and bilirubin levels in cases of megaloblastic anemia and to correlate it with severity of vitamin b12 deficiency. Method: A case control study was done on 200 people with 100 cases having megaloblastic anemia and 100 normal healthy controls during a span of 1 year. Required biochemical studies were done and data was tabulated in predesigned proforma and assessed. The continues variables were presented as means and compared by unpaired t test. Correlation was assessed by Pearson correlation coefficient. Results: The mean LDH level in cases (5076.1 u/l) was very significantly (p value <0.0001) higher than controls (443.6 u/l) and mean bilirubin level was also very significantly higher in cases than controls. On correlation analysis, the levels of both LDH correlated with severity of anemia. Conclusion: Since, LDH and bilirubin both are significantly raised in cases of megaloblastic anemia and also their levels correlates well with the severity of anemia, so they can be used as indirect markers of diagnosis and severity.
Keywords: megaloblastic anemia, lactate dehydrogenase, bilirubin, vitamin B12
Edition: Volume 9 Issue 9, September 2020,
Pages: 412 - 415
How to Cite this Article?
Dr. Shyam Bihari Meena, Dr. Vipul Phogat, Dr. Shyoji Ram Meena, "Diagnostic Role of Lactate Dehydrogenase and Bilirubin Level in Megaloblastic Anemia", International Journal of Science and Research (IJSR), Volume 9 Issue 9, September 2020, pp. 412-415, https://www.ijsr.net/get_abstract.php?paper_id=SR20909194936
How to Share this Article?
Similar Articles with Keyword 'lactate dehydrogenase'
Respiratory Manifestations and Outcome of COVID-19 Positive Patients with CKD
DR Shashibhushan B L | Dr Parvathy S Pillai | Dr Rashmitha M T
CT Chest Severity Index in SARS CoV2 - A Tool to Predict Clinical Outcome
Dr. Brunda M S | Dr. Arushi Mohan | Dr. Abhinaya Shekhar  | Dr. Samriddha Thapa | Dr. Harshadayani Jagdish Kumar | Dr. Shabreen Khanum C R | Dr. Padma L