Downloads: 82 | Views: 94
Research Paper | Anaesthesiology | India | Volume 9 Issue 8, August 2020
Comparison of Intrathecal Buprenorphine and Dexmedetomidine as an Adjuvant to Bupivacaine Heavy for Post-Operative Analgesia in Patients Undergoing Caesarean Section
Dr. Archana Vaghela | Dr. Jaimin Patel | Dr. Bhavana Soni
Abstract: Introduction: Pain relief is very important aspect in postoperative period in parturient. Addition of adjuvants with Bupivacaine for spinal anaesthesia improve the quality of perioperative analgesia. Materials and methods: Each patient was informed about the study and informed consent was taken after approval from institutional ethical committee. This study includes 50 patients of ASA grade I and grade II. The patients were allocated into two groups in each 25 patients included. Group B receive 2.5ml of 0.5 % bupivacaine with 60μg of buprenorphine and Group D 2.5ml of 0.5 % bupivacaine with 5μg of dexmedetomidine intrathecally. The onset time to sensory level, motor block, haemodynamic, sedation, duration of analgesia, motor block and any side effects were noted. APGAR score was used to observed Neonatal outcome. Results: There was no significant difference between groups regarding demographic characteristics and type of surgery. The motor, sensory blockade, time of rescue analgesia and sedation were significantly prolonged in Group D compared to Group B. There was no significant difference found in haemodynamic variables. Neonatal outcome was normal in both groups. Conclusion: Addition of dexmedetomidine causes prolonged anaesthesia and analgesia. So there was reduction in need for sedation and rescue analgesics when compared with buprenorphine.
Keywords: Bupivacaine, Buprenorphine, Dexmedetomidine, Caesarean section, Spinal anaesthesia
Edition: Volume 9 Issue 8, August 2020,
Pages: 1193 - 1197
Similar Articles with Keyword 'Bupivacaine'
Comparative Studies, Anaesthesiology, India, Volume 11 Issue 11, November 2022Pages: 414 - 416
Dexmedetomidine as an Adjuvant to Levobupivacaine in Paravertebral Block for Postoperative Analgesia after Breast Cancer Surgery
Dr. Mudhanuru Bhargava Mallesh Yadav | Dr. G. Vijaya Lakshmi  | Dr. Anil Kumari  | Dr. Joga Aparna 
Comparative Studies, Anaesthesiology, India, Volume 12 Issue 2, February 2023Pages: 928 - 936
Comparison of Effect of Preservative Free Ketamine and Magnesium Sulphate used as an Adjuvant to 0.5 % Hyperbaric Bupivacaine in Orthopaedic Lower Limb Surgeries under Spinal Anaesthesia - A Prospective Double Blind Randomised Control Study
Pratheev E  | Arpita Bhargava  | Ritushree Sharma