International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064

Downloads: 109

Review Papers | Biomedical Sciences | India | Volume 9 Issue 7, July 2020

Polycystic Ovary Syndrome (PCOS) Symptoms, Causes & Treatments - A Review

Nobendu Mukerjee

Abstract: Polycystic ovary syndrome [PCOS] is the most common endocrinopathy of women in reproductive age. An association between PCOS and type-1 endometrial cancer has often been reported in the literature. The prolonged anovulation with consequent continued secretion of estrogen unopposed by progesterone may enhance the development and growth of this malignancy, particularly in young women. Hypersecretion of luteinizing hormone [LH], chronic hyperinsulinemia and increased serum insulin-like growth factor [IGF] levels may represent risk factors for endometrial cancer. However, data available in the literature do not allow a meta-analysis to be carried out to calculate an estimate of the relative risk of endometrial cancer in women with PCOS. Anecdotal cases of low-grade endometrial stromal sarcoma and carcinosarcoma have been reported in association with prolonged unopposed estrogen stimulation, and in particular with PCOS. A few studies have addressed the possibility of an association between PCOS and epithelial ovarian cancer risk. Women with PCOS produce higher-than-normal amounts of male hormones. This hormone imbalance causes them to skip menstrual periods and makes it harder for them to get pregnant.

Keywords: androgenetic alopecia, cyproterone acetate, drospirenone, polycystic ovary syndrome, spironolactone, MAPK/ERK/p38 signaling pathway, metformin, clomiphene citrate, clomiphene citrate resis

Edition: Volume 9 Issue 7, July 2020,

Pages: 1949 - 1957

How to Cite this Article?

Nobendu Mukerjee, "Polycystic Ovary Syndrome (PCOS) Symptoms, Causes & Treatments - A Review", International Journal of Science and Research (IJSR),, Volume 9 Issue 7, July 2020, 1949 - 1957

How to Share this Article?

Enter Your Email Address

Similar Articles with Keyword 'alopecia'

Downloads: 104

Review Papers, Biomedical Sciences, United Kingdom, Volume 7 Issue 1, January 2018

Pages: 1119 - 1123

A Review on the Effects of Chemotherapy Drugs and Cooling alone or in Combination on the Cell Cycle

Wafaa Al Tameemi, Mothana A. Hassan

Share this Article

Downloads: 118 | Monthly Hits: ⮙1

Informative Article, Biomedical Sciences, India, Volume 7 Issue 4, April 2018

Pages: 1130 - 1134

Hair Follicle Cloning and Gene Therapy

Pallavi Kaulwar, Shrikant G. Pathak

Share this Article

Similar Articles with Keyword 'acetate'

Downloads: 76

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 2, February 2021

Pages: 131 - 135

Oral Administration of Ethyl Acetate Extract of Sanrego (Lunasia amara Blanco) Wood Increased the Number of Leydig Cells and Testosterone Levels in Old Male Wistar Rats (Rattus norvegicus)

Florindo Cardoso Gomes, Wimpie Pangkahila, I Gusti Made Aman

Share this Article

Downloads: 150

Research Paper, Biomedical Sciences, India, Volume 6 Issue 8, August 2017

Pages: 437 - 442

Novel Tumor Markers of Breast Cancer Patients

Alibha Rawat, N. Ganesh

Share this Article