International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064

Downloads: 102

Research Paper | Medical Science | India | Volume 9 Issue 8, August 2020

Cytogenetic and Microarray Analysis of Eunuchs

Tushar N Chauhan, R. K. Patel, Jigar Suthar

Abstract: Eunuchs are people with abnormal sexual behaviour, uncharacterized sex, neither male nor female and known as transgender people. They have abnormal or non-functional external genitalia. XX male syndrome, also known as De la Chapelle syndrome, is a rare congenital intersex condition where an individual with a 46, XX karyotype has phenotypically male characteristics that vary among cases. SRY gene plays an important role in sex differentiation along with other genes such as SOX9, DAX1, WT1, WNT4 and FGF9. The rarest form of the genetic abnormality- 46, XX sex reversal is caused by random genetic mutations. Materials and Methods: Peripheral blood leukocyte culture and microarray analysis were performed for the present study. Results: Two cases of 46, XX male sex reversal without the SRY gene was reported out of 36 unrelated blood samples of eunuchs. None of the patients had autosomal sex reversal hence neither autosomal nor X-linked genes are involved in it. Conclusion: Sex reversal may be one of the causes of the development of eunuchism.

Keywords: Sex reversal, Eunuch, XX-male, SRY gene, microarray, karyotyping

Edition: Volume 9 Issue 8, August 2020,

Pages: 681 - 686

How to Cite this Article?

Tushar N Chauhan, R. K. Patel, Jigar Suthar, "Cytogenetic and Microarray Analysis of Eunuchs", International Journal of Science and Research (IJSR),, Volume 9 Issue 8, August 2020, 681 - 686

How to Share this Article?

Enter Your Email Address

Similar Articles with Keyword 'Sex'

Downloads: 0

Research Paper, Medical Science, India, Volume 10 Issue 6, June 2021

Pages: 1335 - 1339

Comparative Study of Efficacy of Epley's and Semont?s Maneuver in the Treatment of Benign Paroxysmal Positional Vertigo in a Tertiary Hospital

Simon C Vincent, Kuldeep Moras

Share this Article

Downloads: 1

Research Paper, Medical Science, Morocco, Volume 10 Issue 7, July 2021

Pages: 1379 - 1383

Penile Prosthesis and Couple Satisfaction: A Prospective Study

RABII Redouane, BALAR Khalid, MOUSSAB Rachid, MESBAHI Meryem, BELHAJ Karim

Share this Article

Similar Articles with Keyword 'reversal'

Downloads: 99

Case Studies, Medical Science, Senegal, Volume 8 Issue 12, December 2019

Pages: 1433 - 1437

Contribution of Thoracic Angioscanner in the Diagnosis of Pulmonary Embolism: About 90 Cases at the Aristide Le Dantec Hospital of Dakar

H. Deme, M. Diouf, L. G. Akpo, N. Badji, F.G. Niang, A. D. Diop, Y. Kasse, A. Mbaye, I. Faye, P. A. Diop, M. C. Fall, M. N. Mbengue, O. Sano, F. K. Aw, S. Ba, E H. Niang

Share this Article

Downloads: 178

Research Paper, Medical Science, Brazil, Volume 9 Issue 3, March 2020

Pages: 432 - 439

Study of Fragility Syndrome in Elderly from an University Open to Third Age

Filho Celso A. B., Nascimento Henrique A, Morais Lanna T. G. De, Amorim Rayane C. De, Silva Victoria R., Fernandes Luciana C., Viviane Lemos Silva Fernandes

Share this Article