Research Paper | Anaesthesiology | India | Volume 9 Issue 6, June 2020
Hands Free Anesthesia: Target Controlled Infusion Systems
Dr Zohra Mehdi
The target of every form of drug delivery is achieving and maintaining a therapeutic time course of drug effect, while avoiding adverse effects. Intravenous (IV) drugs are usually given using standard dosing guidelines either as a bolus dose or by continuous infusion. Bolus doses are typically administered with a handheld syringe and infusions with an infusion pump. The only patient covariate that is incorporated into a dose calculation is the body weight, while other parameters like age, sex, creatinine clearance etc are often ignored because of the complex mathematical relationship of these covariates while dosing. Target-controlled infusion (TCI) is a technique of infusing IV drugs to achieve a user-defined, predicted (target) drug concentration in a specific body compartment or tissue of interest. TCI systems can rapidly titrate response as necessary, can easily alter depth of anaesthesia and also maintain steady concentrations when required. The potential benefit to clinicians is the more precise titration of anesthetic drug effect. TCI systems can also be instructed to overshoot the desired concentration in the plasma to accelerate the rate of onset of drug effect.
Keywords: Anesthesia, Infusion System
Edition: Volume 9 Issue 6, June 2020
Pages: 1171 - 1175
How to Cite this Article?
Dr Zohra Mehdi, "Hands Free Anesthesia: Target Controlled Infusion Systems", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SR20612113423, Volume 9 Issue 6, June 2020, 1171 - 1175
67 PDF Views | 67 PDF Downloads
Similar Articles with Keyword 'Anesthesia'
A Comparative Evaluation of Dexmedetomidine versus Midazolam-Fentanyl for Sedation in Ocular Surgeries under Peribulbar Anaesthesia in Children
Dr. Ramakant Sharma, Dr. Alaka Purohit
Auditory Evoked Potentials: A Reliable Guide to Sedation Levels during General Anethesia
Dr Gurucharan Dasari
Anesthesia Induced Developmental Neurotoxicity (AIDN)
Dr Gurucharan Dasari
Anesthetic Concerns in a Patient with Carcinoma Cheek with Absolute Trismus (Zero Mouth Opening) in a 60 Year Old Lady Posted for Wide Excision of Cheek with Hemi Mandibulectomy and Radical Neck Dissection with Myocutaneous Flap Cover
Dr A Rubia Sultana, Dr Murali Prabhakar, Dr Bhaskar
Intubation Difficulty Scale and Influence of Preoperative Airway Assessment Tests in Elective Surgical Patients
Mohammad Sharif Oria, Omran Omar Amarkhil, Husniya Azim, Sultan Ahmad Halimi