International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064




Downloads: 102

Case Studies | Medical Science | India | Volume 9 Issue 6, June 2020


Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination

Piyush Dhawan | Mahendra Kumar [17] | Prasan Kumar Panda | Bharat Vadlamani


Abstract: Neuro-Osseo-sarcoidosis is a rare presentation and tubercular etiology for sarcoidosis is always debatable. We had a middle-aged woman who presented with symptoms and signs suggestive of chronic meningitis including arachnoiditis and was further investigated for probable etiologies with CSF study being equivocal with high proteins and normal cell counts. She had contact family history of tuberculosis. On imaging studies, MRI and MRI lumbosacral spine revealed lesions consistent with neuro-osseo-sarcoidosis following which biopsy taken from bony lesions was inconclusive. CT-chest done to see pulmonary involvement suggested typical features of sarcoidosis. She was started with corticosteroids and she had improvement in her symptoms and regain of appetite suggesting response to treatment and confirms diagnosis of disseminated sarcoidosis. On follow-up after 1months, there was deterioration further in general condition with appearance of new onset focal seizures and neuroimaging suggested multiple ring lesions consistent with tuberculoma along with chest CT imaging showing cavitatory lesions in left lung. However, there were partial/complete regressions of all previous lesions in brain and chest. Bronchoalveolar lavage suggested positive acid-fast bacilli and CBNAAT confirmed rifampicin sensitive Mycobacterium tuberculosis. Hence coexistence of tuberculosis and sarcoidosis, reactivation of tuberculosis, or tuberculosis as probable etiology for sarcoidosis could not be ruled out.


Keywords: Antitubercular therapy, Disseminated tuberculosis, Granulomatous disease, Osseous sarcoidosis, Steroids


Edition: Volume 9 Issue 6, June 2020,


Pages: 417 - 419


How to Cite this Article?

Piyush Dhawan, Mahendra Kumar, Prasan Kumar Panda, Bharat Vadlamani, "Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination", International Journal of Science and Research (IJSR), Volume 9 Issue 6, June 2020, pp. 417-419, https://www.ijsr.net/get_abstract.php?paper_id=SR20529194531

How to Share this Article?

Enter Your Email Address




Similar Articles with Keyword 'Steroids'

Downloads: 0

Research Paper, Medical Science, India, Volume 11 Issue 7, July 2022

Pages: 1359 - 1364

A Clinicopathological Study of Refractory Lupus Nephritis in Tertiary Care Hospital in North East India

Dr. Manjuri Sharma | Benjamin Sangma | Prodip Kumar Doley | Gayatri Pegu

Share this Article

Downloads: 1

Research Paper, Medical Science, India, Volume 10 Issue 5, May 2021

Pages: 1052 - 1055

RITUXIMAB in Lupus Related Autoimmune Haemolytic Anemia

Mohnish Patel | Prashant Chotalia | Puja Srivastava | Sapan C Pandya

Share this Article


Top