Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

Case Studies | Medical Science | India | Volume 9 Issue 6, June 2020

Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination

Piyush Dhawan, Mahendra Kumar, Prasan Kumar Panda, Bharat Vadlamani

Neuro-Osseo-sarcoidosis is a rare presentation and tubercular etiology for sarcoidosis is always debatable. We had a middle-aged woman who presented with symptoms and signs suggestive of chronic meningitis including arachnoiditis and was further investigated for probable etiologies with CSF study being equivocal with high proteins and normal cell counts. She had contact family history of tuberculosis. On imaging studies, MRI and MRI lumbosacral spine revealed lesions consistent with neuro-osseo-sarcoidosis following which biopsy taken from bony lesions was inconclusive. CT-chest done to see pulmonary involvement suggested typical features of sarcoidosis. She was started with corticosteroids and she had improvement in her symptoms and regain of appetite suggesting response to treatment and confirms diagnosis of disseminated sarcoidosis. On follow-up after 1months, there was deterioration further in general condition with appearance of new onset focal seizures and neuroimaging suggested multiple ring lesions consistent with tuberculoma along with chest CT imaging showing cavitatory lesions in left lung. However, there were partial/complete regressions of all previous lesions in brain and chest. Bronchoalveolar lavage suggested positive acid-fast bacilli and CBNAAT confirmed rifampicin sensitive Mycobacterium tuberculosis. Hence coexistence of tuberculosis and sarcoidosis, reactivation of tuberculosis, or tuberculosis as probable etiology for sarcoidosis could not be ruled out.

Keywords: Antitubercular therapy, Disseminated tuberculosis, Granulomatous disease, Osseous sarcoidosis, Steroids

Edition: Volume 9 Issue 6, June 2020

Pages: 417 - 419

Share this Article

How to Cite this Article?

Piyush Dhawan, Mahendra Kumar, Prasan Kumar Panda, Bharat Vadlamani, "Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SR20529194531, Volume 9 Issue 6, June 2020, 417 - 419

68 PDF Views | 58 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Granulomatous disease'

Research Paper, Medical Science, India, Volume 9 Issue 10, October 2020

Pages: 1736 - 1737

Sarcoidosis: An Unusual Case of Pleural Effussion

Dr Deepak Rosha, Dr Ishan Gupta

Share this Article

Case Studies, Medical Science, India, Volume 9 Issue 6, June 2020

Pages: 417 - 419

Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination

Piyush Dhawan, Mahendra Kumar, Prasan Kumar Panda, Bharat Vadlamani

Share this Article

Similar Articles with Keyword 'Steroids'

Case Studies, Medical Science, India, Volume 9 Issue 6, June 2020

Pages: 417 - 419

Tubercular Neuro-Osseous-Pulmonary Sarcoidosis - A Challenging Combination

Piyush Dhawan, Mahendra Kumar, Prasan Kumar Panda, Bharat Vadlamani

Share this Article

Case Studies, Medical Science, India, Volume 9 Issue 5, May 2020

Pages: 1695 - 1697

Irrational Corticosteroid Use Causing Extensive Striae Distensae

Dr. Deepak. E.R, Dr. C. Ganesan, Dr. J. Naga Haritha

Share this Article

Research Paper, Medical Science, India, Volume 7 Issue 10, October 2018

Pages: 915 - 919

Intravitreal Triamcinolone Acetonide in Diabetic Macular Edema

Dr. Kabita Bora Baishya, Dr. Suprio Kumar Datta

Share this Article

Case Studies, Medical Science, Guinea, Volume 8 Issue 4, April 2019

Pages: 1135 - 1137

Sjogren Syndrome: Description of 4 Cases Guinean

Conde Kaba, Garba Mahaman Salissou, Niasse Moustapha

Share this Article

Research Paper, Medical Science, India, Volume 9 Issue 5, May 2020

Pages: 1386 - 1392

Clinical and Histopathological Spectrum of Childhood Onset Nephrotic Syndrome- Prospective Study

Dr. Sam Rao Athota, Dr. K. Sai Harisha, Dr. G. Prasad

Share this Article
Top