Downloads: 129
Survey Paper | Microbiology | India | Volume 9 Issue 4, April 2020
Comparative Study of Japanese Encephalitis, Live Attenuated Vaccine Potency by CCID50 and PFU Method
Sood Seema | Bhardwaj Arun | Tandon Shweta
Abstract: Japanese Encephalitis, live attenuated vaccine is a cell culture derived (Primary Hamster Kidney), live attenuated vaccine based on the SA 14-14-2 strain manufactured by China and is imported to India. The potency of a live vaccine is typically expressed in terms of the number of infectious unit of viruses contained in human doses using a specified tissue culture substrate. Both BHK-21 cell line as well as vero cell line shows good susceptibility for JE Virus. WHO recommends the use of BHK-21 cell line or any other cell line acceptable to the National Control Authority. In the present study the potency of the JE vaccine was performed by CCID50 & PFU method using Vero cell line.
Keywords: CCID50, Vero cell line, BHK-21 cell line, Cytopathic effect, PFU, Vaccines
Edition: Volume 9 Issue 4, April 2020,
Pages: 969 - 976
Comparative Study of Japanese Encephalitis, Live Attenuated Vaccine Potency by CCID50 and PFU Method
How to Cite this Article?
Sood Seema, Bhardwaj Arun, Tandon Shweta, "Comparative Study of Japanese Encephalitis, Live Attenuated Vaccine Potency by CCID50 and PFU Method", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SR20415151936, Volume 9 Issue 4, April 2020, 969 - 976, #ijsrnet
How to Share this Article?
Similar Articles with Keyword 'Cytopathic effect'
Downloads: 104
Research Paper, Microbiology, Egypt, Volume 4 Issue 2, February 2015
Pages: 2082 - 2088Serological and Molecular Typing of Avian Pathogenic E. Coli Originating from Outbreaks of Colibacillosis in Chicken Flocks
Sarah A. Yousef | Ammar A. M. | Ahmed D. A. [2]
Downloads: 148
Research Paper, Microbiology, Iraq, Volume 6 Issue 6, June 2017
Pages: 766 - 769Virological Study about Avipox virus in Local Birds of Iraq
Hussein A. Mohammed Al. Bayati