Remimazolam: Revolutionizing Tiva
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

Views: 173 , Downloads: 146 | CTR: 84 % | Weekly Popularity: ⮙1

Review Papers | Anaesthesiology | India | Volume 9 Issue 3, March 2020

Remimazolam: Revolutionizing Tiva

Dr Chandrasekhar Krishnamurti

Drugs having a short duration of action and early recovery are often the preferred choice for sedation. Propofol fits into this category but it has safety issues such as decrease of blood pressure, respiratory depression, vascular pain and a high susceptibility of the drug to bacterial growth. (1, 2) It also lacks a reversal agent. Midazolam has a weaker circulatory suppressive effect than propofol, but it is rarely used for the induction and maintenance of general anaesthesia because of its longer duration of action (40 min), variable onset and offset of sedative effect. (3, 4, 5) Remimazolam (CNS 7056, C₂₁H₁₉BrN₄O₂) is a novel benzodiazepine created out of a soft drug development technique known as rational drug designing. It is an ultrashort-acting intravenous sedative-anesthetic currently in Phase III clinical trials as a safe and effective option for procedural sedation. Remimazolam does not produce injection site pain. Its safety of clinical use is further increased by the availability of benzodiazepine antagonist Flumazenil. High extra hepatic clearance also confers little scope for metabolic interactions with other drugs in the liver and its propensity to cause apnea is very low. (6)

Keywords: Remimazolam, TIVA

Edition: Volume 9 Issue 3, March 2020

Pages: 579 - 581

Share this Article

How to Cite this Article?

Dr Chandrasekhar Krishnamurti, "Remimazolam: Revolutionizing Tiva", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SR20309151425, Volume 9 Issue 3, March 2020, 579 - 581

173 PDF Views | 146 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'TIVA'

Views: 23 , Downloads: 14 | CTR: 61 % | Weekly Popularity: ⮙3

Research Paper, Anaesthesiology, India, Volume 10 Issue 2, February 2021

Pages: 1522 - 1528

Occupational Risks, Safety and Well Being among Anesthesiologists

Dr Illuri Surya Teja, Dr Chandrasekhar Krishnamurti

Share this Article

Views: 16 , Downloads: 15 | CTR: 94 % | Weekly Popularity: ⮙9

Research Paper, Anaesthesiology, India, Volume 10 Issue 3, March 2021

Pages: 1601 - 1606

Aspects of Orofacial Pain

Dr Devulapalli D.S.S.S. Sarma, Dr Chandrasekhar Krishnamurti M.D.

Share this Article

Views: 33 , Downloads: 31 | CTR: 94 % | Weekly Popularity: ⮙6

Research Paper, Anaesthesiology, India, Volume 10 Issue 2, February 2021

Pages: 1030 - 1035

A Review of Thromboelastography

Dr Penmatsa Swathi, Dr Chandrasekhar Krishnamurti

Share this Article

Views: 49 , Downloads: 39 | CTR: 80 % | Weekly Popularity: ⮙9

Research Paper, Anaesthesiology, India, Volume 10 Issue 3, March 2021

Pages: 232 - 245

Oral Clonidine vs Oral Gabapentin for Obtunding Hemodynamic Response to Laryngoscopy and Tracheal Intubation

Dr. Aravinthan Mamallan, Dr. U. G. Thirumaaran

Share this Article

Views: 111 , Downloads: 89 | CTR: 80 % | Weekly Popularity: ⮙1

Research Paper, Anaesthesiology, India, Volume 9 Issue 5, May 2020

Pages: 1566 - 1572

Pre Emptive Analgesia: A New Dimension in Pain Management

Dr Chandrasekhar Krishnamurti, Dr Mounika Jonnavittula

Share this Article
Top