International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064

Research Paper | Microbiology | Sudan | Volume 9 Issue 2, February 2020

Assessments of Sero-Detection of Herpes Simplex virus-1 and 2 Antibodies IgG and IgM among Spontaneous Recurrent Miscarriage Women; Case Control Study in Gezira State 2018

Rasha Ageeb ALshaikh Mohammed, Awad Mohammed Awad, Nadir Musa Khalid Abuzeid

Background: Recurrent miscarriage is a critical problem and it takes to increase during current decade, herpes simplex virus-1 and 2 have relation with recurrent miscarriage according to some previous study conducted in many countries. Objectives: The aim of present study to Sero-detection of herpes simplex virus -1 and 2 (IgG and IgM antibodies) by using ELISA techniques among women with recurrent miscarriage in Gezira state and assessment of other risk factors according to questionnaire. Method: Analytic - case control study (45 women in each arm) was conducted at Wad Madani teaching hospital Department of Obstetrics gynecological, AlGezira state, Sudan. The cases were women with recurrent miscarriage and controls were healthy pregnant women (non-miscarriage).Herpes simplex virus1 and 2 antibodies were analyzed in the sera of the entire participant using ELISA techniques. Results: Ninety women were enrolled in each arm of study. Miscarriage and non miscarriage serum IgG sero-positivity for HSV-1 44 (97.1 %) vs 41 (91.1 %) and HSV-2 is 13 (28.9 %) vs 4 (8.9 %) by ELISA. There was no significant difference in miscarriage serum IgM sero-positivity for HSV-1 16 (35.6 %) vs 6 (13.3 %) and borderline 2 (2.2 %) vs 2 (4.4 %) by ELISA. In logistic regression analysis of the predictors for miscarriage (OR=2.047, 95 %Cl=.179-23.4.57, P.value 0.04).IgM sero-positivity were at risk for miscarriage.Other significant risk factors include microcytic hypochromic anemia, vaginal bleeding, pre-eclampsia and familyhistory. Conclusion: In the current study herpes simplex virus -1 and 2 IgG sero-positivity is associated with miscarriage. Using ELISA techniques are presumptive tools to confirm the results. Preventive measure should be implemented. Further research in needed.

Keywords: HSV-1 and 2, antibodies, recurrent miscarriage women, ELISA

Edition: Volume 9 Issue 2, February 2020

Pages: 1519 - 1523


How to Cite this Article?

Rasha Ageeb ALshaikh Mohammed, Awad Mohammed Awad, Nadir Musa Khalid Abuzeid, "Assessments of Sero-Detection of Herpes Simplex virus-1 and 2 Antibodies IgG and IgM among Spontaneous Recurrent Miscarriage Women; Case Control Study in Gezira State 2018", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SR20213180900, Volume 9 Issue 2, February 2020, 1519 - 1523

22 PDF Views | 24 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'antibodies'

Case Studies, Microbiology, India, Volume 4 Issue 5, May 2015

Pages: 2138 - 2142

Seroprevalence and Clinical Correlates of Toxoplasma Gondii Infection among Patients in Tertiary Care Hospital

Gohel Tejash, Turbadkar Dilip, Baveja Sujata

Share this article

Review Papers, Microbiology, India, Volume 4 Issue 6, June 2015

Pages: 2775 - 2780

Ebola Virus Disease: The Global Worry

Mythri B.A., Arati.K

Share this article

Research Paper, Microbiology, Nigeria, Volume 5 Issue 3, March 2016

Pages: 1255 - 1259

Seroprevalence of IgM Antibodies to Dengue Fever Virus among Patients Presenting with Symptoms of Fever in Some Hospitals in Kaduna State, Nigeria

O. A. Bello, M. Aminu, E. D. Jatau

Share this article

Research Paper, Microbiology, Egypt, Volume 4 Issue 5, May 2015

Pages: 660 - 664

Preparation and Field Evaluation of Mycoplasma bovisMembrane Vaccine in Egypt

Sabry Eissa

Share this article

Research Paper, Microbiology, Bangladesh, Volume 8 Issue 11, November 2019

Pages: 513 - 516

Foetomaternal Morbidity and Foetal Outcome of Cytomegalo Virus Seropositive Pregnant Women: Experience from Bangladesh

Dr. Md Azmir Jahid Hossain, Dr. Md Ruhul Amin, Dr. Farhana Yasmin, Dr. Ashraful Haque

Share this article

Similar Articles with Keyword 'recurrent miscarriage women'

Research Paper, Microbiology, Sudan, Volume 9 Issue 2, February 2020

Pages: 1431 - 1435

Assessments of Sero-Detection of HEV Antibodies IgG and IgM among Spontaneous Recurrent Miscarriage Women Case Control Study in Gezira State 2018

Nisreen Elgaily Ibrahim Mohammed Ahmed, Nadir Musa Khalil Abuzeid

Share this article

Research Paper, Microbiology, Sudan, Volume 9 Issue 2, February 2020

Pages: 1519 - 1523

Assessments of Sero-Detection of Herpes Simplex virus-1 and 2 Antibodies IgG and IgM among Spontaneous Recurrent Miscarriage Women; Case Control Study in Gezira State 2018

Rasha Ageeb ALshaikh Mohammed, Awad Mohammed Awad, Nadir Musa Khalid Abuzeid

Share this article

Similar Articles with Keyword 'ELISA'

Case Studies, Microbiology, India, Volume 4 Issue 5, May 2015

Pages: 2138 - 2142

Seroprevalence and Clinical Correlates of Toxoplasma Gondii Infection among Patients in Tertiary Care Hospital

Gohel Tejash, Turbadkar Dilip, Baveja Sujata

Share this article

Research Paper, Microbiology, Nigeria, Volume 5 Issue 3, March 2016

Pages: 1255 - 1259

Seroprevalence of IgM Antibodies to Dengue Fever Virus among Patients Presenting with Symptoms of Fever in Some Hospitals in Kaduna State, Nigeria

O. A. Bello, M. Aminu, E. D. Jatau

Share this article

M.Tech / M.E / PhD Thesis, Microbiology, Iraq, Volume 6 Issue 7, July 2017

Pages: 1483 - 1487

Bacteriological and Immunological Study of Rheumatoid Arthritis

Dr. Suaad Khalil Ibrahim, Teeba Fares Hadi

Share this article

Research Paper, Microbiology, Egypt, Volume 4 Issue 5, May 2015

Pages: 660 - 664

Preparation and Field Evaluation of Mycoplasma bovisMembrane Vaccine in Egypt

Sabry Eissa

Share this article

Research Paper, Microbiology, India, Volume 4 Issue 1, January 2015

Pages: 374 - 377

Detection of Cymbidium Mosaic Virus (CYMV) on Vanda Plants

D. R. Sudha, G. Usha Rani

Share this article

Top