International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 47

Research Paper | Health and Medical Sciences | India | Volume 9 Issue 12, December 2020


Evaluation of Salivary Cotinine Level in Tobacco Chewers - A Case-Control Study

Dr. Laxmikanth Chatra | Dr. Muhsina CH | Dr. Prashanth Shenoy | Dr. Veena KM | Dr. Rachana V Prabhu


Abstract: Aim and objective: To compare the salivary cotinine level in tobacco chewers and non chewers and to corelate cotinine level with the duration of tobacco chewing habit. Methodology: The study was conducted in 94 subjects, divided into two groups, control Group and study group, with 47 participants in each group. The salivary samples were collected from all the participants and cotinine concentration was measured using competitive Elisa method. Result: The mean salivary cotinine levels in group 1 and group 2 was 6.649 and 92.8040 respectively. When mean values were compared between the groups the values were found to be statistically highly significant, and study also showed there is no correlation between the salivary cotinine level and duration of the tobacco chewing habit. Conclusion: The result of our study showed the increased levels of cotinine in chewers as compared to non-chewers. No association was noted between cotinine levels and duration of chewing. Salivary cotinine level proved to be a useful biomarker of recent tobacco use and can be used in epidemiological studies and tobacco cessation programs.


Keywords: Cotinine, Tobacco chewers, Biomarker, Elisa


Edition: Volume 9 Issue 12, December 2020,


Pages: 1391 - 1393

Evaluation of Salivary Cotinine Level in Tobacco Chewers - A Case-Control Study


How to Cite this Article?

Dr. Laxmikanth Chatra, Dr. Muhsina CH, Dr. Prashanth Shenoy, Dr. Veena KM, Dr. Rachana V Prabhu, "Evaluation of Salivary Cotinine Level in Tobacco Chewers - A Case-Control Study", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SR201221202616, Volume 9 Issue 12, December 2020, 1391 - 1393, #ijsrnet

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