Downloads: 2 | Monthly Hits: ⮙1
Research Paper | Pathology | India | Volume 11 Issue 3, March 2022
Evaluation of Human Papilloma Virus Infection Using Immunohistochemistry in Histologically Diagnosed Oral, Oropharyngeal and Laryngeal Cancers
Reema Sachdev | Seema Baxi
Abstract: Introduction: Oral, oropharynx and laryngeal cancers are reported to be associated with HPV. There is no data available regarding percentage of HPV induced head and neck cancers from most areas of Gujarat. Hence, this study was planned. Aims and Objectives: 1) To estimate overall propotion of HPV in oral, oropharyngeal and laryngeal squamous carcinomas. 2) To assess association of age, gender and site specific prevalence of oral, oropharyngeal and laryngeal squamous carcinomas related to HPV infection. Materials and Methods: A prospective hospital based study of HPV by immunohistochemistry was done on biopsies and surgical specimen of 24 consecutive cases of histologically proven oral, oropharyngeal and laryngeal squamous cell cancers. Inclusion criteria: All the oral biopises and surgical specimens received in pathology department which were histologically proven for oral, oropharyngeal, laryngeal squamous cell cancers. Exclusion criteria: Family history of oral, oropharyngeal and laryngeal squamous cell cancers and previously taken HPV vaccine. Results: Total Proportion of HPV in HNSCC was 25% in Bhavnagar region. Males were most commonly affected; most common age group was between 41-60 years and most common site of HPV associated HNSCCs was oropharynx. Conclusion: HPV is detected in HNSCCs in Bhavnagar region.
Keywords: HPV, IHC
Edition: Volume 11 Issue 3, March 2022,
Pages: 1396 - 1399
How to Cite this Article?
Reema Sachdev, Seema Baxi, "Evaluation of Human Papilloma Virus Infection Using Immunohistochemistry in Histologically Diagnosed Oral, Oropharyngeal and Laryngeal Cancers", International Journal of Science and Research (IJSR), Volume 11 Issue 3, March 2022, pp. 1396-1399, https://www.ijsr.net/get_abstract.php?paper_id=SR201211153210
How to Share this Article?
Similar Articles with Keyword 'HPV'
Relationship between High Risk Human Papilloma Virus and Immune Expression of Mutated Retinoblastoma (Rb) Protein in Oral Cancer
Faris Mergheni Eltoum | Hussain Gadelkarim Ahmed 
HPV in Oral Squamous Cell Carcinoma-Review Article
T. V. Rajalakshmi Rakshanaa  | Dr. M. D. Brundha Suresh