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Research Paper | Biochemistry | India | Volume 9 Issue 11, November 2020
Anti Inflammatory Activity of Ferulic Acid against Carrageenan and Formalin Induced Paw Edema in Swiss Albino Mice
Saratchandran A. Divakaran, Anitha CT
The anti-inflammatory activity of ferulic acid (FA) was evaluated using carrageenan and formalin-induced paw edema models in Swiss albino mice. The anti-inflammatory activity was found to be dose dependent in both paw edema model. Administration of the FA showed significant (p˂0.001) inhibition of paw edema, 28 % and 37.5 % on 6th hour at the doses of 100 and 200 mg/kg body weight respectively in Carrageenan induced paw edema model. Similar pattern of paw edema inhibition was seen in formalin-induced paw edema model. The maximum percentage inhibition in paw edema was 31.4 % and 46.87 % on 6 th day at the doses of 100 and 200 mg/kg, respectively. The results of present study demonstrate that FA possess significant anti-inflammatory potential.
Keywords: anti-inflammatory activity, paw edema, carrageenan, formalin
Edition: Volume 9 Issue 11, November 2020
Pages: 788 - 792
How to Cite this Article?
Saratchandran A. Divakaran, Anitha CT, "Anti Inflammatory Activity of Ferulic Acid against Carrageenan and Formalin Induced Paw Edema in Swiss Albino Mice", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SR201112102033, Volume 9 Issue 11, November 2020, 788 - 792
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