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Research Paper | Medical Science | India | Volume 9 Issue 11, November 2020

Pneumonia Severity Index and CURB-65 score as a Predictor of In-Hospital Mortality in Acute Exacerbation of COPD

Dr. Pankaj Kumar Singh | Dr. Mohit Bhatnagar | Dr. Sandeep Nimba Deore | Dr. Mandeep Joshi | Dr. Tausif Ahmed | Dr. Subhrojyoti Bhowmick | Dr. Shreya Verma

Abstract: Aim and Objective To investigate the role of Pneumonia Severity Index (PSI) and confusion, Urea, Respiratory Rate, Blood Pressures core (CURB-65) in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disorder with Reference to Mortality Methods In our study a total of 100 patients of COPD with acute exacerbation were included in the study from tertiary care centre, Kolkata for a period of 12 months from December 2015 to November 2016. Results In our study, overall in hospital mortality was 21 %, while mortality in age groups 50-65, 66-80 and >80 were respectively 3.3 %, 28.3 % and 29.41 %. Hence advanced age was associated with significant increase in mortality. The mortality among risk classes of PSI like II, III, IV and V was respectively 0 %, 0 %, 22.22 % and 78.57 % respectively. The percentage of mortality increased significantly as the PSI score increases (p value ≤ 0.001). The mortality associated with the low, intermediate, and high risk classes of CURB-65 was respectively 4.17 %, 14 % and 50 %. Mortality increased with an increase in score demonstrating a significant relation between the two (p value = 0.006). Conclusion Chronic obstructive pulmonary disease (COPD) is a global public health problem and a significant cause of chronic morbidity and mortality worldwide. Infectious are at least 75-80 % of acute COPD exacerbations. Our study detected 21 % in-hospital mortality. A PSI score of >130 i. e. risk class V as well as CURB-65 score of more than equal to 3 i. e. group 3, were strong predictors of in-hospital mortality.

Keywords: Chronic Obstructive Pulmonary Disease, Exacerbation, Mortality, Prognosis

Edition: Volume 9 Issue 11, November 2020,

Pages: 247 - 253

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