International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064

Downloads: 87

Research Paper | Medical Science | Indonesia | Volume 9 Issue 10, October 2020

Antihistamine in Pediatrics Dermatology

Ni Kadek Setyawati | Luh Wira Pusvitasari | Luh Made Mas Rusyati | Dewi Gotama

Abstract: Antihistamine commonly used in cases of pediatrics dermatology. Skin diseases are generally found in at least 30 % of all visits to pediatrics clinics. Pediatrics population is heterogeneous, which range from preterm neonates to adulthood after puberty. Each group has a higher complex physiological, developmental and psychological characteristic than the adult population, this description varies widely from neonates to adulthood. H (1) -antihistamines are generally used to relieve itching and other symptoms due to atopic dermatitis, urticaria, allergic rhinitis, or other diseases that have high morbidity in children. H (1) -antihistamines can be categorized into first-generation and second-generation antihistamines. The first generation H (1) -antihistamines penetrate the blood brain barrier and thus have a significant effect for the central nervous system giving them a sedative effect. The adverse effect of H (1) -antihistamines such as sedation, central nervous system disturbances, gastrointestinal complaints, anticholinergic effect, cardiac arrhythmias, moreover hypersensitivity reactions. Second generation of H (1) -antihistamines are the drugs of choice for allergic responses because of their high selectivity to H1 receptors, high efficacy, and minimal side effects. The half-life in plasma depends on drug metabolism and elimination processes in the body. The process is the same in children and adults, but it is said to occur more rapidly in several cases of children with certain antihistamines. Adverse reaction in children reported against multiple antihistamine administered, although antihistamine is an important drug for use, should not forget that antihistamine also can cause severe reaction and not completely safe drugs.

Keywords: antihistamine, pediatrics, allergy, dermatology

Edition: Volume 9 Issue 10, October 2020,

Pages: 1602 - 1607

How to Cite this Article?

Ni Kadek Setyawati, Luh Wira Pusvitasari, Luh Made Mas Rusyati, Dewi Gotama, "Antihistamine in Pediatrics Dermatology", International Journal of Science and Research (IJSR), Volume 9 Issue 10, October 2020, pp. 1602-1607,

How to Share this Article?

Similar Articles with Keyword 'pediatrics'

Downloads: 0

Research Paper, Medical Science, India, Volume 11 Issue 1, January 2022

Pages: 1342 - 1347

Clinical Profile and Outcomes of Mechanically Ventilated Children in Pediatric Intensive Care Units - A Single Centre Prospective Study

Dr. Maddi Prakash Kumar | Dr. C. N. Mohan Chandran | Dr. Sudharsan N E | Dr. Sai Susmitha Dasari | Dr. Teja Sureddi | Dr. Gopi Krishna Nimmagadda

Share this Article

Downloads: 0

Case Studies, Medical Science, Indonesia, Volume 11 Issue 10, October 2022

Pages: 986 - 989

Anesthesia Considerations in Pediatrics with Wilms' Tumor: A Case Report

Marthen Luther King Elmas | Cynthia Dewi Sinardja [2]

Share this Article