Downloads: 106
Research Paper | Zoology | India | Volume 3 Issue 9, September 2014
Effects of Acute and Chronic Lead Exposure on Kidney Lipid Peroxidation and Antioxidant Enzyme Activities in BALB-C Mice (Mus Musculus)
Sushma Sharma, Balbinder Singh
Extensive and unmonitored use of lead in developing and industrialised countries is posing a serious threat to human health. Prolonged exposure of a sub-lethal dose of this toxicant is closely related to its accumulation in various soft tissues and its interference with bio elements that hamper several physiological processes. Present study was carried out to investigate the toxic effects of lead acetate on biochemical parameters in the kidney of Swiss-albino mice with a trial to evaluate their self recovery from this toxicant in respective parameters without any supplement. Therefore eighteen normal mice showing no sign of morbidity were divided into three groups of 6 animals each. Lead acetate was given orally to mice for 40 days. First group served as control and was given normal saline solution as vehicle. Mice of second group were given daily 10mg/kg bw of lead. Whereas third group was given daily 150mg/kg bw of lead. The mice of both the groups were sacrificed by cervical dislocation after day 1, 40 and 80 along with control animals. The findings indicated that exposure for 40 days resulted in significant increase (p
Keywords: Lead acetate, oxidative stress, kidney
Edition: Volume 3 Issue 9, September 2014
Pages: 1564 - 1567
How to Cite this Article?
Sushma Sharma, Balbinder Singh, "Effects of Acute and Chronic Lead Exposure on Kidney Lipid Peroxidation and Antioxidant Enzyme Activities in BALB-C Mice (Mus Musculus)", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SEP14425, Volume 3 Issue 9, September 2014, 1564 - 1567
Similar Articles with Keyword 'Lead acetate'
Downloads: 106
Research Paper, Zoology, India, Volume 3 Issue 9, September 2014
Pages: 1564 - 1567Effects of Acute and Chronic Lead Exposure on Kidney Lipid Peroxidation and Antioxidant Enzyme Activities in BALB-C Mice (Mus Musculus)
Sushma Sharma, Balbinder Singh
Downloads: 134
Research Paper, Zoology, India, Volume 3 Issue 8, August 2014
Pages: 355 - 357Recovery of Alanine aminotransferase from Lead exposed freshwater fish, Anabas testudineus (Bloch, 1792)
Shaikh Afsar, R. P. Mali
Similar Articles with Keyword 'oxidative stress'
Downloads: 101
Research Paper, Zoology, India, Volume 9 Issue 4, April 2020
Pages: 1709 - 1713Prophylactic Action of Flaxseed Oil against Cyclophosphamide Induced Oxidative Stress in Mice Liver
Dr. Brij Mohan Singh
Downloads: 106
Research Paper, Zoology, India, Volume 3 Issue 9, September 2014
Pages: 1564 - 1567Effects of Acute and Chronic Lead Exposure on Kidney Lipid Peroxidation and Antioxidant Enzyme Activities in BALB-C Mice (Mus Musculus)
Sushma Sharma, Balbinder Singh
Downloads: 115 | Weekly Hits: ⮙4 | Monthly Hits: ⮙11
Research Paper, Zoology, India, Volume 4 Issue 9, September 2015
Pages: 881 - 884Antioxidant Activity of Root of Achyranthes Aspera and its Comparison with Melatonin in Recovery of Oxidative Stress
Nisreen Husain, Anil Kumar
Downloads: 130
Research Paper, Zoology, India, Volume 6 Issue 12, December 2017
Pages: 656 - 661Protective Effect of Adhatoda Vasica Extract on Gamma Radiation Induced Oxidative Stress in Mice Biceps Muscle
Sushma Sharma, Anupam Pundir
Downloads: 131 | Weekly Hits: ⮙2
Research Paper, Zoology, India, Volume 5 Issue 9, September 2016
Pages: 765 - 767Analysis of Oxidative Stress Responses in Copper Exposed Catla catla
Gutha Rajasekar, Dr. C Venkatakrishnaiah
Similar Articles with Keyword 'kidney'
Downloads: 98
Research Paper, Zoology, India, Volume 10 Issue 3, March 2021
Pages: 33 - 39Cadmium Toxicity in Kidney Ultrastructure of Freshwater Fish, Oreochromis mossambicus (Peters)
Meenakshi Sundaresan
Downloads: 102
Research Paper, Zoology, India, Volume 5 Issue 4, April 2016
Pages: 1975 - 1979Effect of Chlorpyrifos on Some Biochemical Constituents in Liver and Kidney of Fresh Water Fish,Channa Gachua (F.Hamilton)
Padmini Kadam, Rajaram Patil
Downloads: 106
Research Paper, Zoology, India, Volume 3 Issue 9, September 2014
Pages: 1564 - 1567Effects of Acute and Chronic Lead Exposure on Kidney Lipid Peroxidation and Antioxidant Enzyme Activities in BALB-C Mice (Mus Musculus)
Sushma Sharma, Balbinder Singh
Downloads: 107
Research Paper, Zoology, India, Volume 4 Issue 10, October 2015
Pages: 1669 - 1675Mercury Toxicity in Hormonal Effects to Fresh Water Fish Cirrhinus Mrigala
Dr. Y. Thangam, M. Manju
Downloads: 120
Research Paper, Zoology, India, Volume 5 Issue 4, April 2016
Pages: 1816 - 1820Protective Effect of Andrographis paniculata against Thioacetamide Cytotoxicity in Liver and Kidney of Albino Rat
Patil R. N, Salunkhe A. J