International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




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Research Paper | Immunology | United States of America | Volume 5 Issue 5, May 2016


Burden of Lupus Nephritis among Patients Managed in Routine Clinical Practices in Europe

Siva Narayanan MS MHS


Abstract: Assessing the characteristics of patients with Lupus Nephritis (LN) in comparison to those without LN among patients with systemic lupus erythematosus (SLE) could help portray LN disease burden. A multi-center chart review of adult SLE patients was conducted among rheumatologists/internal medicine physicians in UK/France/Germany/Italy/Spain (EU5) to collect data on disease characteristics and treatment patterns.168 LN patients and 569 non-LN patients with SLE were analyzed. Among LN/Non-LN cohorts, % currently receiving care in in-patient setting was14.9/8.8, % hospitalized >=1 in the past-year was49.4/29.7. Clinical burden (patients experiencing a flare, low C3/C4, higher SELENA-SLEDAI scores) and humanistic burden (diminished ability to perform every-day tasks, interact fully with family and friends, or work/keep employment) was higher among LN cohorts. Factors influencing the observed burden, including the therapeutic strategies used in these geographies warrant further investigation to manage LN optimally.


Keywords: Lupus Nephritis, Burden, Flares, Hospitalizations, Europe


Edition: Volume 5 Issue 5, May 2016,


Pages: 1364 - 1367

Burden of Lupus Nephritis among Patients Managed in Routine Clinical Practices in Europe


How to Cite this Article?

Siva Narayanan MS MHS, "Burden of Lupus Nephritis among Patients Managed in Routine Clinical Practices in Europe", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=NOV163718, Volume 5 Issue 5, May 2016, 1364 - 1367, #ijsrnet

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