International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064



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Research Paper | Chemistry | Iraq | Volume 5 Issue 3, March 2016


Synthesis, Characterize and Antimicrobial Study of New Chalcones and Pyrazole Derivatives from Progesterone

Nisreen Kais Abood | Hiba Hayder Ibraheem


Abstract: The aim of this work synthesized a new series of chalcones and pyrazole derivatives from the progesterone, the new steroidal synthesized by the claisen-Schmidt condensation reaction, were react progesterone with different aromatic substituted aldehyde in presence sodium hydroxide afforded chalcones derivatives (1-6). Cyclized the chalcone derivatives by reaction with hydrazine hydrate to afforded pyrazole derivatives (7-12). All synthesized compounds were characterized by measurement melting point, FT-IR spectral, Elemental Analysis and some of them by 1H-NMR spectral and Antimicrobials activities.


Keywords: Progesterone, Chalcone, Pyrazole, Antimicrobial, Biological activity


Edition: Volume 5 Issue 3, March 2016,


Pages: 833 - 836


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How to Cite this Article?

Nisreen Kais Abood, Hiba Hayder Ibraheem, "Synthesis, Characterize and Antimicrobial Study of New Chalcones and Pyrazole Derivatives from Progesterone", International Journal of Science and Research (IJSR), Volume 5 Issue 3, March 2016, pp. 833-836, https://www.ijsr.net/get_abstract.php?paper_id=NOV161838



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