Research Paper | Chemistry | India | Volume 5 Issue 4, April 2016
Spectroscopic Investigation on the Interaction between 4-Amino Salicylic Acid (PAS) with Bovine Serum Albumin (BSA)
Mamali Priyadarshinee | Bairagi C. Mallick 
Abstract: PAS (4-amino salicylic acid) is a potentialantimicrobial drug used for the treatment of Mycobacterium tuberculosisdrug resistance. Its interaction with bovine serum albumin (BSA) is important to understand the mechanism of drug-protein interactions and its effectiveness to treat the drug resistance. The binding of PAS with BSA, investigatedby UV-visible and fluorescence measurements clearly indicates the conformational stability of the protein, Further, FT-IR and CD spectroscopic methods support the results with inceasing secondary structure content of the protein in the presence of drug.
Keywords: Bovine serum albumin BSA, 4-aminosalicylic acid PAS, fluorescence, FT-IR and CD spectroscopy
Edition: Volume 5 Issue 4, April 2016,
Pages: 573 - 576
How to Cite this Article?
Mamali Priyadarshinee, Bairagi C. Mallick, "Spectroscopic Investigation on the Interaction between 4-Amino Salicylic Acid (PAS) with Bovine Serum Albumin (BSA)", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=NOV161826, Volume 5 Issue 4, April 2016, 573 - 576, #ijsrnet
How to Share this Article?
Similar Articles with Keyword 'fluorescence'
New Spectrophotometric and Spectrofluorimetric Methods for Determination of Prazosin HCl in API and Drug Product
Hanan M. Elwy | Taghreed A. Mohammed
Modification of the Photocatalytic Activity of Zinc Oxide by Doping Silver
Amjed M. Odeh | Ahmed S. Ferhod | Abbas J. Lafta