International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



Research Paper | Biological Engineering | Morocco | Volume 5 Issue 2, February 2016

Optimal Control of a Discrete HIV Model with Two Classes of Antiretroviral Therapy

Amine Bouaine, Mostafa Rachik

The aim of this work is to set an adequate discrete HIV models taking into consideration two antiretroviral Pro- tease Inhibitors and Reverse Transcriptase Inhibitors. Furthermore, we investigate optimal control strategies in order to reduce infected cells and infectious virions. Using an iterative method, three numerical simulations are carried out, compared and interpreted to confirm the validity of the model and prove the performance of the op- timization strategies. Finally, we improve the patients lives by minimizing serious side effects and also reducing drug costs and duration of treatments

Keywords: Optimal control, Therapy, Discrete HIV model, Pontryagins Maximum Principle

Edition: Volume 5 Issue 2, February 2016

Pages: 1670 - 1677

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How to Cite this Article?

Amine Bouaine, Mostafa Rachik, "Optimal Control of a Discrete HIV Model with Two Classes of Antiretroviral Therapy", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=NOV161473, Volume 5 Issue 2, February 2016, 1670 - 1677

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