International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064

Downloads: 119

Research Paper | Medicine Science | Albania | Volume 4 Issue 12, December 2015

Treatment Response in Schizophrenia

Irena Thoma, Anastas Suli

Schizophrenia is characterized by a differential response to antipsychotic treatment based on stage of illness, with evidence that shorter duration of untreated psychosis is associated with greater antipsychotic response. The aim of the study was to assess the clinical response to clozapine. The patients included in this study were those participating in a prospectively designed clozapine monitoring program (n = 202 subjects) who completed at least 52 weeks of treatment and had complete data records at Psychiatric Hospital, University Hospital Centre ?Mother Theresa? in Tirana, Albania over the period 2013 -2014. In the study participated 102 subjects with a mean age 44.2 (?10.7) years with a range 22-74 years old. Thirty five (34.3%) were women and 67 (65.7%) men meeting both DSM-IV criteria for schizophrenia and Kane's criteria for drug-resistance.27 (26.8%) patients were classified as responders, 45 (44%) being refractory (Clozapine responders) and 30 (29.2%) super-refractory. The super-refractory group had the highest scores for totals of BPRS (p<0.01) in all visits. Treatment resistant schizophrenia remains a major personal tragedy and a public health problem.

Keywords: schizophrenia, clozapine, super refractory, response,

Edition: Volume 4 Issue 12, December 2015

Pages: 1811 - 1813

Share this Article

How to Cite this Article?

Irena Thoma, Anastas Suli, "Treatment Response in Schizophrenia", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=NOV152231, Volume 4 Issue 12, December 2015, 1811 - 1813

Enter Your Email Address


Similar Articles with Keyword 'schizophrenia'

Downloads: 118

Research Paper, Medicine Science, United Kingdom, Volume 9 Issue 6, June 2020

Pages: 1893 - 1903

Examination of Cognitive Deficits Produced by Sub-Chronic Ketamine Exposure in Rats

Christopher Wood, Mohammed Shoib

Share this Article

Downloads: 117

Research Paper, Medicine Science, Bulgaria, Volume 7 Issue 4, April 2018

Pages: 1267 - 1269

Onychomycosis among Patients with Schizophrenia and Comorbid Substance Use Disorders

Petranka Chumpalova, Valentin Valtchev, Maya Stoimenova-Popova, Ludmil Tumbev

Share this Article

Similar Articles with Keyword 'response'

Downloads: 84

Research Proposals or Synopsis, Medicine Science, Saudi Arabia, Volume 5 Issue 12, December 2016

Pages: 2052 - 2056

Review of the Level of Awareness Towards Occupational Injury among Restorative Staff at Selected Dental Clinics, Saudi Arabia

Dr. Duaa Adil Sharaf Sharaf

Share this Article

Downloads: 87

Case Studies, Medicine Science, Bulgaria, Volume 3 Issue 10, October 2014

Pages: 1332 - 1334

Possibility of Combined Assessment of Biomarkers in Early Parkinsons Disease

Dimitar Kochev, Julia Petrova, Maria Petrova, Dimo Krastev, Lachezar Traikov

Share this Article
Top