International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 110

Research Paper | Microbiology | Saudi Arabia | Volume 4 Issue 11, November 2015


Antibacterial Behavior of Weed Plants from Aseer, Saudi Arabia and Their Possible Mode of Action

Mohamed Hashem, Saad A. Alamri, Ashia A. Shathan, Sulaiman A. Alrumman, Mahmoud F.M. Moustafa


Abstract: With steadily growing of the microbial resistance against the classical antibiotics, searching new and effective natural antimicrobial agents become crucial. The study introduces new herbal extracts as antibacterial agents against both Gram-positive and Gram-negative bacteria. In vitro antibacterial activity of 15 weed plant species, collected from Aseer region, Saudi Arabia and their effective minimum inhibitory concentrations (MIC) were determined. The possible mode of action of the most effective plant extracts was investigated. Crude extracts of the investigated species were prepared using three organic solvents. Bacillus subtilis and Proteus vulgaris were used as test organisms to evaluate the antibacterial effect of the crude extracts and their (MIC). Examination with scanning electron microscopy of the treated bacteria as well as analysis of the plant extract using GC-MS were performed to explore the possible mode of action. Foeniculum vulgare, Xanthium spinosum, Abutilon pannosum, Solanum incanum, Forsskaolea tenacissima and Brassica deflexa were the most effective plants among the fifteenth tested species. Scan electron micrographs (SEM) revealed a clear morphological malformation in the bacterial shapes. This supports our hypothesis that extracts could alter the bacterial cell membrane permeability causing plasmolysis. GC-MS analysis of plant extracts proved the presence of aliphatic and aromatic compounds, whereas, the number and types of these compounds depended on the type of the organic solvent. The chloroform extracts of Xanthium spinosum, Abutilon pannosum are very promising antibacterial agents against both Gram-positive and Gram-negative bacteria. Further investigation is recommended to scale up and validate the application of the test plant extracts.


Keywords: Antibacterial, Weed plants, SEM, GC-MS, Saudi Arabia, Xanthium spinosum, Abutilon pannosum


Edition: Volume 4 Issue 11, November 2015,


Pages: 2491 - 2499


How to Cite this Article?

Mohamed Hashem, Saad A. Alamri, Ashia A. Shathan, Sulaiman A. Alrumman, Mahmoud F.M. Moustafa, "Antibacterial Behavior of Weed Plants from Aseer, Saudi Arabia and Their Possible Mode of Action", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=NOV151692, Volume 4 Issue 11, November 2015, 2491 - 2499

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Antibacterial'

Downloads: 186

Research Paper, Microbiology, India, Volume 6 Issue 1, January 2017

Pages: 296 - 299

Antibacterial behaviour of Common Winter Season Weeds on Human Pathogens in Doon Valley, Uttarakhand, India

Maneesha Singh, Rashmi Bist

Share this Article

Downloads: 4 | Monthly Hits: ⮙1

Research Paper, Microbiology, India, Volume 10 Issue 8, August 2021

Pages: 253 - 256

In vitro Evaluation of Antimicrobial Activity of Moringa oleifera Lam. Extracts against Pathogens Causing Wound Infection

Mridula G Nair, Dr. Rohini P Patil

Share this Article

Similar Articles with Keyword 'SEM'

Downloads: 110

Review Papers, Microbiology, India, Volume 4 Issue 1, January 2015

Pages: 1297 - 1302

Alleviating Salt Stress in Crop Plants through Salt Tolerant Microbes

Avinash D Patil

Share this Article

Downloads: 116

Survey Paper, Microbiology, India, Volume 4 Issue 1, January 2015

Pages: 2474 - 2478

Study of Knowledge, Attitude and Practices Regarding Hygiene among Abattoir Workers in Kano State Metropolitan, Nigeria

Junaidu Yakubu M, Bhagavandas M, Yushau Umar

Share this Article

Similar Articles with Keyword 'GCMS'

Downloads: 44

Research Paper, Microbiology, Nigeria, Volume 6 Issue 12, December 2017

Pages: 1484 - 1492

Phytochemical Determination and In Vitro Antimicrobial Activity of Crude Ethanolic Extract of Stem Bark of Boswellia dalzielii

Baha'uddeen Salisu Dandashire; Abdulkadir Magaji Magashi; Bashir Abdulkadir

Share this Article

Downloads: 143 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Microbiology, India, Volume 5 Issue 4, April 2016

Pages: 251 - 256

Activated Sludge: Decolorization and Degradation of Textile Dye Reactive Orange HE2R

Pratibha S. Patil

Share this Article

Similar Articles with Keyword 'Saudi Arabia'

Downloads: 103

Research Paper, Microbiology, Saudi Arabia, Volume 4 Issue 5, May 2015

Pages: 1736 - 1743

Prevalence of Vaginal Candidiasis among Pregnant Women Attending Al-Hada Military Hospital, Western Region, Taif, Saudi Arabia

Dr. Khadijah Yosif Al-Aali

Share this Article

Downloads: 112

Research Paper, Microbiology, Saudi Arabia, Volume 4 Issue 1, January 2015

Pages: 2359 - 2362

Molecular Identification of Aeromonas spp. Collected from Taif Province of Saudi Arabia

Othman M. Alzahrani

Share this Article
Top