International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064




Downloads: 116

Research Paper | Medicine Science | Egypt | Volume 4 Issue 11, November 2015


Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt

Adel AM Ghorab | Walid M Afifi | Yasser Elnaggar | Amal A. Zidan MD


Abstract: Background HCV infection and type 2 diabetes mellitus are two chronic conditions which contribute to a significant morbidity and mortality. Egypt has the highest hepatitis C virus (HCV) prevalence in the world (14.7 %). The drivers of the HCV epidemic in Egypt are not well understood, but the mass parenteral antischistosomal therapy (PAT) campaigns in the second half of the 20th century are believed to be the determinant of the high prevalence. The mutual relationship between diabetes and increased HCV infection may be due to the association of HCV with hepatic steatosis, insulin resistance and decrease of adiponectine synthesis as well as the nature of diabetes and its inherent complications and/or frequent parental exposure. Objective There are many studies in the past done on frequency of diabetes in HCV infection and the average was 13.84 % prevalence of type 2 diabetes mellitus in HCV seropositive patients, but little number of studies evaluated the prevalence of HCV in diabetics. Our aim is to determine the prevalence of HCV infection in diabetics in Sharkia Governorate and to explore the predominant risk factors for HCV infection and its relation to some demographic parameters of this locality. Subjects and methods A cross sectional randomized study was conducted to 642 patients, regardless of gender, body weight, educational level or socioeconomic levels, at multicentre managing diabetic patients at Sharkia governorate. All patients were subjected to detection of HCV-ab by third generation ELISA and HBA1C level. Results The prevalence of HCV infection among diabetic patients at Sharkia governorate approximates 38.7 %. Higher prevalence was detected among patients between 45 & 65 years old, low socioeconomic level, low educational level, those who shared personal utensils, those with family members infected with HCV, patients who previously transfused, previous hospitalized, previously received parenteral anti-bilharzial therapy and those receiving insulin injections. Conclusion As high as 39 % of diabetic patients at Sharkia Governorate are HCV-infected. Apart from classic risk factors, the most significant independable factors associated with development of HCV infection in diabetic patients are low socioeconomic standard and low educational level. Previous blood transfusion, family members infected with HCV, parenteral antibilharzial treatment, sharing personal utensils and previous hospitalization may play also a role.


Keywords: Hepatitis C virus, diabetic patients, Prevalence


Edition: Volume 4 Issue 11, November 2015,


Pages: 1713 - 1720


How to Cite this Article?

Adel AM Ghorab, Walid M Afifi, Yasser Elnaggar, Amal A. Zidan MD, "Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt", International Journal of Science and Research (IJSR), Volume 4 Issue 11, November 2015, pp. 1713-1720, https://www.ijsr.net/get_abstract.php?paper_id=NOV151497

How to Share this Article?






Similar Articles with Keyword 'Hepatitis C virus'

Downloads: 112

Research Paper, Medicine Science, Egypt, Volume 6 Issue 5, May 2017

Pages: 1187 - 1192

Amino Acid Substitution in Hepatitis C Virus Core and Genetic Variation in Interleukin 28? Gene and their Correlation to Interferon Treatment Failure in Chronic HCV Egyptian Patients

Nashwa El-Khazragy [2] | Maiada A. Hussien | Mohamed A. El-Mordy | Amany M. Maher

Share this Article

Downloads: 124

Research Paper, Medicine Science, Sudan, Volume 5 Issue 10, October 2016

Pages: 1258 - 1261

Hepatitis C Viral Infection among Health Care Workers at Dialysis Centers in Khartoum State, Sudan

Eltagi Abdalla Mohammed Abdalla [2] | Kamil Merrghani Ali Shappan

Share this Article


Top