Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064



Research Paper | Medicine Science | Egypt | Volume 4 Issue 11, November 2015

Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt

Adel AM Ghorab, Walid M Afifi, Yasser Elnaggar, Amal A. Zidan MD

Background HCV infection and type 2 diabetes mellitus are two chronic conditions which contribute to a significant morbidity and mortality. Egypt has the highest hepatitis C virus (HCV) prevalence in the world (14.7 %). The drivers of the HCV epidemic in Egypt are not well understood, but the mass parenteral antischistosomal therapy (PAT) campaigns in the second half of the 20th century are believed to be the determinant of the high prevalence. The mutual relationship between diabetes and increased HCV infection may be due to the association of HCV with hepatic steatosis, insulin resistance and decrease of adiponectine synthesis as well as the nature of diabetes and its inherent complications and/or frequent parental exposure. Objective There are many studies in the past done on frequency of diabetes in HCV infection and the average was 13.84 % prevalence of type 2 diabetes mellitus in HCV seropositive patients, but little number of studies evaluated the prevalence of HCV in diabetics. Our aim is to determine the prevalence of HCV infection in diabetics in Sharkia Governorate and to explore the predominant risk factors for HCV infection and its relation to some demographic parameters of this locality. Subjects and methods A cross sectional randomized study was conducted to 642 patients, regardless of gender, body weight, educational level or socioeconomic levels, at multicentre managing diabetic patients at Sharkia governorate. All patients were subjected to detection of HCV-ab by third generation ELISA and HBA1C level. Results The prevalence of HCV infection among diabetic patients at Sharkia governorate approximates 38.7 %. Higher prevalence was detected among patients between 45 & 65 years old, low socioeconomic level, low educational level, those who shared personal utensils, those with family members infected with HCV, patients who previously transfused, previous hospitalized, previously received parenteral anti-bilharzial therapy and those receiving insulin injections. Conclusion As high as 39 % of diabetic patients at Sharkia Governorate are HCV-infected. Apart from classic risk factors, the most significant independable factors associated with development of HCV infection in diabetic patients are low socioeconomic standard and low educational level. Previous blood transfusion, family members infected with HCV, parenteral antibilharzial treatment, sharing personal utensils and previous hospitalization may play also a role.

Keywords: Hepatitis C virus, diabetic patients, Prevalence

Edition: Volume 4 Issue 11, November 2015

Pages: 1713 - 1720

Share this Article

How to Cite this Article?

Adel AM Ghorab, Walid M Afifi, Yasser Elnaggar, Amal A. Zidan MD, "Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=NOV151497, Volume 4 Issue 11, November 2015, 1713 - 1720

69 PDF Views | 48 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Hepatitis C virus'

Research Paper, Medicine Science, Egypt, Volume 6 Issue 5, May 2017

Pages: 1187 - 1192

Amino Acid Substitution in Hepatitis C Virus Core and Genetic Variation in Interleukin 28? Gene and their Correlation to Interferon Treatment Failure in Chronic HCV Egyptian Patients

Nashwa El-Khazragy, Maiada A. Hussien, Mohamed A. El-Mordy, Amany M. Maher

Share this Article

Research Paper, Medicine Science, Egypt, Volume 4 Issue 11, November 2015

Pages: 1713 - 1720

Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt

Adel AM Ghorab, Walid M Afifi, Yasser Elnaggar, Amal A. Zidan MD

Share this Article

Research Paper, Medicine Science, Sudan, Volume 5 Issue 10, October 2016

Pages: 1258 - 1261

Hepatitis C Viral Infection among Health Care Workers at Dialysis Centers in Khartoum State, Sudan

Eltagi Abdalla Mohammed Abdalla, Kamil Merrghani Ali Shappan

Share this Article

Research Paper, Medicine Science, Albania, Volume 5 Issue 12, December 2016

Pages: 484 - 487

Distribution of HCV Genotype among the Patients Treated for Chronic Hepatitis C in Albania

Stela Taci, Sonela Xinxo, Jovan Basho

Share this Article

Research Paper, Medicine Science, Albania, Volume 6 Issue 4, April 2017

Pages: 2217 - 2219

Prevalence of HCV Virus among Thalassemia Patients in Albania

Pranvera Doci, Tatjana Nurka, Edi Dragusha, Renata Shkjezi

Share this Article

Similar Articles with Keyword 'diabetic patients'

Research Paper, Medicine Science, Saudi Arabia, Volume 6 Issue 1, January 2017

Pages: 2450 - 2458

Awareness on Diabetes Complications and Protective Measures in Makkah Region among Known Diabetic Patients: A Cross-Sectional Survey

Anoud R. Omer; Abdullah A. Alghamdi; Rakan A. AlYamani; Salman H. Alqurash; Abdulaziz A. Alshikh; Roa'a A. Alshaik; Mohamed E. Salih; Anees A Sindi

Share this Article

Research Paper, Medicine Science, India, Volume 3 Issue 12, December 2014

Pages: 1979 - 1980

To Study the Surgical Complications of Diabetes and their Management in the Rural Population

Dr Murali Mohan R

Share this Article

Research Paper, Medicine Science, India, Volume 3 Issue 6, June 2014

Pages: 672 - 678

Effectiveness of Self Instructional Module on the Knowledge Regarding Diabetic Diet among Diabetic Patients

Santhosh Thomas, Vaishali R Mohite

Share this Article

Research Paper, Medicine Science, Egypt, Volume 4 Issue 11, November 2015

Pages: 1713 - 1720

Prevalence of Hepatitis C Infection among Diabetics Type 2 at Sharkia Governorate, Egypt

Adel AM Ghorab, Walid M Afifi, Yasser Elnaggar, Amal A. Zidan MD

Share this Article

Research Paper, Medicine Science, India, Volume 5 Issue 12, December 2016

Pages: 1966 - 1968

Assessment of Serum Lipids in Type II Diabetes Male and Female Patients

Dinky Gajiwala, Malini Andrade

Share this Article

Similar Articles with Keyword 'Prevalence'

Research Paper, Medicine Science, India, Volume 3 Issue 6, June 2014

Pages: 1591 - 1598

Increasing Prevalence of Chronic Obstructive Pulmonary Disease;Tuberculosis; Lung Cancer and Rising Environmental Oestrogen

Elizabeth JeyaVardhini Samuel, Nagarajan Natarajan

Share this Article

Research Paper, Medicine Science, Albania, Volume 4 Issue 3, March 2015

Pages: 2213 - 2215

Autism and Seisures in Children Admitted in a Tertiary Hospital

Armand Shehu, Aida Bushati, Valentina Tashko

Share this Article

Research Paper, Medicine Science, India, Volume 3 Issue 6, June 2014

Pages: 2144 - 2147

Prevalence of Unnatural Death among Reproductive Aged Females in Varanasi Area India

Awdhesh Kumar, Surendra Kumar Pandey

Share this Article

Research Paper, Medicine Science, Macedonia, Volume 4 Issue 7, July 2015

Pages: 1965 - 1967

Analysis of Radicular Dental Calcifications According to the Shape

Pavlina Aleksova

Share this Article

Research Paper, Medicine Science, Macedonia, Volume 4 Issue 7, July 2015

Pages: 2476 - 2478

Prevalence of Coronal Pulp Stones in Maxillary First and Second Molars

Pavlina Aleksova

Share this Article
Top