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Comparative Studies | Obstetrics and Gynecology | India | Volume 12 Issue 2, February 2023
Immediate Versus Delayed Induction with PGE2 Gel in Term Premature Rupture of Membranes: Comparative Study of Maternal Outcome
Dr. Reena Pant | Dr Ram Pyari Saini | Dr. Santosh Saini | Dr. Priyanka Singh 
Abstract: Introduction: As 10% of pregnancies result in premature membrane rupture at term, it can cause complications, both maternal and neonatal, so early diagnosis and proper management is important. The purpose of our study to analyse and compare maternal outcome in Immediate Versus Delayed Induction with PGE 2 gel in Premature Rupture of Membranes at term. Material And Methods: A randomized, controlled comparative study was conducted from April 2021 to February 2022 in the Department of Obstetrics and Gynecology, SMS Medical College, Jaipur.160 cases of premature rupture of membranes (80 cases in each group) were randomly allocated to either immediate induction (Group A) or delayed induction (Group B), with gestational age between 37to 40 weeks. All women with premature rupture of membranes at term were admitted in labour room and history was elicited regarding time of rupture of membranes, duration and amount of leaking with general, systemic and obstetric examination and follow-up for progress of labour and maternal outcome was studied. Results: In our study, 68.7% women in group A had single gel and 31.25% women had repeat gel.21 women (26.25%) in delayed induction group entered in active labor during the waiting period. They did not require induction. Induction with PGE2 gel, immediately after PROM resulted in significantly shorter PROM-delivery interval (14.56hrs vs 23.05 hrs) in comparison to expectant management. However, no significant difference was observed in mode of delivery (vaginal delivery rate 87.5% in immediate induction group and 83.75% in delayed induction group). Conclusion: We conclude that in comparative study of immediate versus delayed induction with PGE2 gel in premature rupture of membranes, the interval from PROM to delivery was higher in delayed induction group than immediate induction group, which was statistically significant. The rate of caesarean section was statistically insignificant among both groups. Among maternal complications, there was no statistically significant difference between both the groups. Hence both methods of management can be used in PROM at term. However, the women in delayed induction group were in labour for many hours.
Keywords: Premature rupture of membranes (PROM), Immediate induction, delayed induction, PGE2 gel
Edition: Volume 12 Issue 2, February 2023,
Pages: 330 - 333
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