International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




Downloads: 1 | Views: 10

Comparative Studies | Anaesthesiology | India | Volume 11 Issue 1, January 2022


A Study Comparing Post-Extubation Hemodynamic Changes with Two Different Doses of Dexmedetomidine

Vivek Chaudhary [3]


Abstract: Introduction: Smokers are one of the at-risk group of patients prone for developing complications during extubation. Objective: Evaluation of post-extubation hemodynamic changes with two different doses of dexmedetomidine. Study design: Prospective randomized study. Method: Sixty patients of ASA physical status I and II were enrolled in the study and divided into 2 groups of 30 each. Group A included 30 patients who received 0.5 ?g/kg of dexmedetomidine in normal saline (Total volume 10 ml). Group B included 30 patients who received 0.75 ?g/kg of dexmedetomidine in normal saline (Total volume 10 ml). Results: The difference in heart rate post extubation between group A and group B was statistically significant immediately post-extubation at 0 min up to 15 min. Thereafter at 30 min up to 120 min post extubation heart rate was comparable between group A and group B. There was statistically significant difference in mean arterial pressure post extubation between group A and group B at 0 minute (P<0.0001), 0.5 min (P<0.0001), 1 minute (P<0.00001), 1.5 min (P<0.0001), 2 min (P<0.0001), 2.5 min (P<0.0001), 3 min (P<0.0001), 3.5 min (P=0.023), 4 min (P=0.002), 4.5 min (P<0.0001) up to 60 min (P=0.000). From 75 min up to 120 min, the mean arterial pressure was comparable between group A and group B Conclusion: Dexmedetomidine with dose of 0.75 ?g/kg is the best dose for maintenance of post-extubation hemodynamic changes.


Keywords: Surgery, dexmedetomidine, extubation


Edition: Volume 11 Issue 1, January 2022,


Pages: 1137 - 1139


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How to Cite this Article?

Vivek Chaudhary, "A Study Comparing Post-Extubation Hemodynamic Changes with Two Different Doses of Dexmedetomidine", International Journal of Science and Research (IJSR), Volume 11 Issue 1, January 2022, pp. 1137-1139, https://www.ijsr.net/get_abstract.php?paper_id=MR22119202632



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