International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 1

Comparative Studies | Ophthalmology | India | Volume 10 Issue 8, August 2021


Evaluation of Correlation among Retinal Nerve Fibre Layer Thickness, Cup Disc Ratio and Perimeteric Indices in Primary Open Angle Glaucoma and Glaucoma Suspects

Preeti Chopra, Manoj Gupta, Sourab Gupta


Abstract: Background: Primary open angle glaucoma (POAG) is the most common type of glaucoma which is considered chronic progressive optic neuropathy, accompanied by a characteristic cupping and atrophy of the optic disc, visual field loss, open angle and no obvious systemic or ocular cause. This study aims at evaluating the correlation between optic disc parameters like Cup - to - Disc Ratio (CDR) and retinal nerve fibre layer thickness (RNFL - T) with Visual Field (VF) defect parameters like Mean Deviation (MD) and Pattern Standard Deviation (PSD) in Primary Open - Angle Glaucoma (POAG) patients and Glaucoma suspects. The study also aims to detect early structural changes in Glaucoma suspects. Methods: This prospective study was conducted at Sankara Eye Hospital, Ludhiana from July 2019 to June 2020.50 eyes with diagnosed POAG and glaucoma suspects were analyzed each. Various optic disc parameters like CDR and RNFL - T was correlated with MD and PSD on perimetery. Results: Mean age of study population was 62.16?8.22 years in glaucoma group and 57.48?9.34 in suspects. There was a statistically significant difference in RNFL - T, CDR and perimeteric findings between POAG and glaucoma suspects (P<0.005). Average RNFL thickness was 67.31?16.56 in POAG and 84.63?3.21 in glaucoma suspect which is statistically significant (P<0.05). There was significant correlation of CDR with RNFL - T and MD in POAG where as no such correlation exist in suspects. Conclusion: There is significant direct correlation between average retinal nerve fibre layer thinning and visual field mean deviation in patients with POAG. Optic disc parameters get severely affected as the stage of glaucoma progresses which has also strong correlation with visual field changes and RNFL thickness. In Glaucoma suspects, these parameters are minimally affected or may show no change at all.


Keywords: Primary open angle glaucoma, Cup-to-Disc Ratio, Retinal nerve fibre layer thickness, Visual Field defect, Mean Deviation, Pattern Standard Deviation, Spectral-domain optical coherence tomography


Edition: Volume 10 Issue 8, August 2021,


Pages: 579 - 584


How to Cite this Article?

Preeti Chopra, Manoj Gupta, Sourab Gupta, "Evaluation of Correlation among Retinal Nerve Fibre Layer Thickness, Cup Disc Ratio and Perimeteric Indices in Primary Open Angle Glaucoma and Glaucoma Suspects", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=MR21812201623, Volume 10 Issue 8, August 2021, 579 - 584

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Primary'

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 5, May 2021

Pages: 997 - 1000

Ocular Surface Squamous Neoplasia - A Clinical Study

L. Rajitha, P. Vishwamitra

Share this Article

Downloads: 1

Case Studies, Ophthalmology, India, Volume 10 Issue 6, June 2021

Pages: 1217 - 1219

Multimodal Imaging in Diagnosis of Choroidal Metastasis in Breast Carcinoma

Sriram Simakurthy, Madhu Kumar, Om Shankar, Ashok Kanakamedla, Jayamadhury Gudimetla, Anurag Shandil

Share this Article

Similar Articles with Keyword 'open'

Downloads: 69

Research Paper, Ophthalmology, India, Volume 9 Issue 10, October 2020

Pages: 919 - 923

Intraocular Pressure Changes after Laser-Assisted In-Situ Keratomileusis versus Photorefractive Keratectomy in Myopic Eyes

B. Aneesha Priya, B.V. Kranthi

Share this Article

Downloads: 72

Research Paper, Ophthalmology, India, Volume 9 Issue 10, October 2020

Pages: 1122 - 1123

Incidence of Glaucoma following Open Globe Injury in a Tertiary Centre

Dr. L. Subha, Dr. M. Jigeesha Preethi

Share this Article

Similar Articles with Keyword 'angle'

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 5, May 2021

Pages: 459 - 461

Curtainless Windows - Approach to a Case of Aniridia

Dr. Manmeet Singh, Dr. Manoj Gupta, Dr. Ruminder Kaur

Share this Article

Downloads: 2

Case Studies, Ophthalmology, India, Volume 10 Issue 6, June 2021

Pages: 467 - 469

Nanophthalmos with Optic Nerve Head Drusen Complicated by Central Serous Chorioretinopathy - A Case Report

Dr Banu Pavitra K, Dr Maninder Singh, Dr Varun Saini, Dr Meenakshi Thakkar

Share this Article

Similar Articles with Keyword 'glaucoma'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 590 - 593

Evaluation of Visual Outcomes and Complications Undergoing Penetrating Keratoplasty

Dr. Saamragye Srivastava, Dr Sanjiv Kumar

Share this Article

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 7, July 2021

Pages: 1446 - 1449

Contrast Sensitivity and Macular Thickness in Patients with Diabetic Macular Odema Following Grid Laser Photocoagulation

Porandla Laxmi Prasanna, Raghu V, Anil Kumar Bhupally, SinduSulekha Chigiri

Share this Article

Similar Articles with Keyword 'Ratio'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1

Survey Paper, Ophthalmology, India, Volume 10 Issue 6, June 2021

Pages: 355 - 360

Cataract Operations by Arvind Medicos Services: Attempts for Awareness and Brining Hope for Commoner from Tamil Nadu, to Enjoy Life, Colors and for Well-being

Dr. Priyanka P. Parihar, Dr. Haripriya A, Dr Sathya Ravilla

Share this Article

Similar Articles with Keyword 'Retinal'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1

Case Studies, Ophthalmology, Morocco, Volume 10 Issue 12, December 2021

Pages: 443 - 446

What Lies Beneath a White Cataract: Uncommon Presentation of Bilateral Ocular Tuberculosis

Hnich H, Berraho A

Share this Article

Similar Articles with Keyword 'nerve'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 5, May 2021

Pages: 459 - 461

Curtainless Windows - Approach to a Case of Aniridia

Dr. Manmeet Singh, Dr. Manoj Gupta, Dr. Ruminder Kaur

Share this Article

Similar Articles with Keyword 'fibre'

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 1149 - 1154

Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patients with and without Diabetic Retinopathy Using OCT (Optical Coherence Tomography)

Anil Kumar Bhupally, Raghu V, Sindu Sulekha Chigiri, Sidhartha A

Share this Article

Downloads: 2

Research Paper, Ophthalmology, India, Volume 10 Issue 8, August 2021

Pages: 830 - 834

Comparison of ONH, GCC and RNFL with SDOCT in Normal, Pre-Perimetry and Glaucoma Patients

Niravkumar Mehta, Mahendrasinh Chauhan, Jigisha Randeri, Suman Kumavat

Share this Article

Similar Articles with Keyword 'layer'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 1149 - 1154

Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patients with and without Diabetic Retinopathy Using OCT (Optical Coherence Tomography)

Anil Kumar Bhupally, Raghu V, Sindu Sulekha Chigiri, Sidhartha A

Share this Article

Similar Articles with Keyword 'thickness'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 7, July 2021

Pages: 1446 - 1449

Contrast Sensitivity and Macular Thickness in Patients with Diabetic Macular Odema Following Grid Laser Photocoagulation

Porandla Laxmi Prasanna, Raghu V, Anil Kumar Bhupally, SinduSulekha Chigiri

Share this Article

Similar Articles with Keyword 'Visual'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 590 - 593

Evaluation of Visual Outcomes and Complications Undergoing Penetrating Keratoplasty

Dr. Saamragye Srivastava, Dr Sanjiv Kumar

Share this Article

Similar Articles with Keyword 'Field'

Downloads: 2

Research Paper, Ophthalmology, India, Volume 10 Issue 8, August 2021

Pages: 830 - 834

Comparison of ONH, GCC and RNFL with SDOCT in Normal, Pre-Perimetry and Glaucoma Patients

Niravkumar Mehta, Mahendrasinh Chauhan, Jigisha Randeri, Suman Kumavat

Share this Article

Downloads: 4

Research Paper, Ophthalmology, India, Volume 10 Issue 7, July 2021

Pages: 360 - 362

Impact of COVID19 Pandemic Lockdown on Ophthalmic Screening of Preterm Neonates in a Tertiary Care Hospital of Uttarakhand

Vatsala Vats, Anjali Chaudhary, Sushobhan Dasgupta, Ashwani Sharma, Himani Gupta, Kavleen Kaur

Share this Article

Similar Articles with Keyword 'defect'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 590 - 593

Evaluation of Visual Outcomes and Complications Undergoing Penetrating Keratoplasty

Dr. Saamragye Srivastava, Dr Sanjiv Kumar

Share this Article

Downloads: 1

Case Studies, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 1036 - 1037

Xerophthalmia with Hypopyon in PEM: A Rare Case Report

Dr. Puja Kedia, Dr. (Mrs) Mamoni Baruah

Share this Article

Similar Articles with Keyword 'Mean'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 5, May 2021

Pages: 997 - 1000

Ocular Surface Squamous Neoplasia - A Clinical Study

L. Rajitha, P. Vishwamitra

Share this Article

Similar Articles with Keyword 'Pattern'

Downloads: 1

Research Paper, Ophthalmology, India, Volume 10 Issue 5, May 2021

Pages: 997 - 1000

Ocular Surface Squamous Neoplasia - A Clinical Study

L. Rajitha, P. Vishwamitra

Share this Article

Downloads: 69

Case Studies, Ophthalmology, India, Volume 9 Issue 5, May 2020

Pages: 970 - 971

A Rare Case of Lacrimo-Auriculo-Dento-Digital (LADD) Syndrome

Dr. Anees Fathima, Dr. Swetha Narayanam, Dr. Madhuri Venigalla, Dr. Sudhakar Potti

Share this Article

Similar Articles with Keyword 'Standard'

Downloads: 67

Research Paper, Ophthalmology, India, Volume 10 Issue 2, February 2021

Pages: 202 - 206

To Study the Efficacy of Difluprednate Ophthalmic Emulsion and Prednisolone Acetate Ophthalmic Suspension on Post-operative Inflammation in Cataract Surgery

Dr Shankar Lal Khajotiya, Dr. Vivek Jain

Share this Article

Downloads: 71

Research Paper, Ophthalmology, India, Volume 9 Issue 10, October 2020

Pages: 875 - 876

A Study of Short Term Rise in Intra Ocular Pressure Following Peri Bulbar Injection of Triamcinolone Acetate

Pankti R Shah, Reema Raval

Share this Article

Similar Articles with Keyword 'optical'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 1149 - 1154

Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patients with and without Diabetic Retinopathy Using OCT (Optical Coherence Tomography)

Anil Kumar Bhupally, Raghu V, Sindu Sulekha Chigiri, Sidhartha A

Share this Article

Similar Articles with Keyword 'coherence'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 1149 - 1154

Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patients with and without Diabetic Retinopathy Using OCT (Optical Coherence Tomography)

Anil Kumar Bhupally, Raghu V, Sindu Sulekha Chigiri, Sidhartha A

Share this Article

Similar Articles with Keyword 'tomography'

Downloads: 0

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 320 - 323

Changes of the Retinal Nerve Fiber Layer in Patients with Mild Cognitive Impairment and Alzheimer's Disease

Christine Susan Roy, Vishali Kandasamy, Chandrasekaran Balasubramanian, Suprithy Somineni Raghupathy

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Ophthalmology, India, Volume 10 Issue 11, November 2021

Pages: 1149 - 1154

Comparison of Retinal Nerve Fibre Layer Thickness in Diabetic Patients with and without Diabetic Retinopathy Using OCT (Optical Coherence Tomography)

Anil Kumar Bhupally, Raghu V, Sindu Sulekha Chigiri, Sidhartha A

Share this Article
Top