International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 124

Research Paper | Chemistry | India | Volume 2 Issue 7, July 2013


Quantum Chemical and Energy Descriptors Based Qsar Studies of Triazines Inhibiting Dihydrofolate Reductase

Mithilesh Tiwari [2] | S. K. Singh [9] | Lakshmi Gangwar [3]


Abstract: Among all the 25 QSAR models PA 1 to PA 25, the number of good QSAR models is 10 whose regression coefficient is greater than 0.7. In all the best 10 QSAR models, heat of formation is common. It means the best descriptor to predict the activities are the heat of formation. Also, the predicted activity obtained by taking heat of formation as single descriptor possesses the good value of regression coefficient which is 0.721430.


Keywords: QSAR, Descriptors, triazines, Dihydrofolate reductase, Steric energy, Heat of formation


Edition: Volume 2 Issue 7, July 2013,


Pages: 96 - 100

Quantum Chemical and Energy Descriptors Based Qsar Studies of Triazines Inhibiting Dihydrofolate Reductase


How to Cite this Article?

Mithilesh Tiwari, S. K. Singh, Lakshmi Gangwar, "Quantum Chemical and Energy Descriptors Based Qsar Studies of Triazines Inhibiting Dihydrofolate Reductase", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=IJSROFF2013304, Volume 2 Issue 7, July 2013, 96 - 100, #ijsrnet

How to Share this Article?

Enter Your Email Address




Similar Articles with Keyword 'QSAR'

Downloads: 1

Research Paper, Chemistry, India, Volume 11 Issue 2, February 2022

Pages: 662 - 670

3D QSAR Analysis of a Set of Pneumocystis carinii DHFR Inhibitors through Pharmacophore Generation Approach

Ruchi Mishra

Share this Article

Downloads: 107

Research Paper, Chemistry, India, Volume 3 Issue 8, August 2014

Pages: 1116 - 1119

QSAR Modeling for Predicting Anti HIV Activity of PETT Derivatives

Megha Choure | Nameeta Bende [3] | Arpan Bharadwaj | Suresh Kumar Verma

Share this Article


Top