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Research Paper | Pathology | India | Volume 2 Issue 2, February 2013
Churg Strauss Syndrome presenting as an Eosinophilic Pleural Effusion
Deepak Nayak M | Sushma V. Belurkar | P. S. Srilatha | Indira Shastry  | Girish Solanke
Abstract: Churg-Strauss syndrome (CSS) is a rare form of systemic vasculitis affecting themedium to small sized vessels. The diagnosis of this disease is based mainly on clinical grounds; comprising of asthma, peripheral blood and tissue eosinophilia, rhinosinusitis and signs of vasculitis in major organs. A 48 year old female patient on treatment for bronchial asthma, presented with a bilateral pleural effusion. The analysis of the fluid revealed an eosinophilic exudate (67%). The additional investigations revealed a raised Immunoglobulin E (IgE) levels and p-ANCA positivity. The presentation of CSS as eosinophilia in body fluids is rare and may herald the onset of the vasculitic phase of the disease.
Keywords: Churg-Strauss syndrome, eosinophilia, pleural effusion
Edition: Volume 2 Issue 2, February 2013,
Pages: 510 - 512
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