International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



Research Paper | Pharmaceutical Science | India | Volume 8 Issue 9, September 2019

Desloratadine Microemulsion Based Solid Lipid Nanoparticles

Varsha Dute, Vijay Mahajan, Amol Deshmukh

In this study, novel and main objective of this research work was to formulate and evaluate the Microemulsion Based Solid lipid Nanoparticles. Desloratadine o/w microemulsion based SLN was prepared to enhanced solubility. Desloratadine saturated solubility determined in different oils, Surfactants and co-surfactants. Sunflower oil, as oily phase and Tween 80 as surfactants and co-surfactants Propylene glycol used for pseudo ternary phase diagrams was constructed to identify the microemulsion regions. Evaluation Drug content, Drug release, Emulsification time, Visual inspection. pH, Particle size. Solid SLN DSC, XRD, SEM, FT-IR, Refractive index, Drug Release.

Keywords: Solid lipid Nanoparticles, Microemulsion, SEM, XRD, Spray drying

Edition: Volume 8 Issue 9, September 2019

Pages: 1274 - 1287

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How to Cite this Article?

Varsha Dute, Vijay Mahajan, Amol Deshmukh, "Desloratadine Microemulsion Based Solid Lipid Nanoparticles", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART2020852, Volume 8 Issue 9, September 2019, 1274 - 1287

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