International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


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Research Paper | Pharmaceutical Science | India | Volume 8 Issue 9, September 2019


Desloratadine Microemulsion Based Solid Lipid Nanoparticles

Varsha Dute, Vijay Mahajan, Amol Deshmukh


Abstract: In this study, novel and main objective of this research work was to formulate and evaluate the Microemulsion Based Solid lipid Nanoparticles. Desloratadine o/w microemulsion based SLN was prepared to enhanced solubility. Desloratadine saturated solubility determined in different oils, Surfactants and co-surfactants. Sunflower oil, as oily phase and Tween 80 as surfactants and co-surfactants Propylene glycol used for pseudo ternary phase diagrams was constructed to identify the microemulsion regions. Evaluation Drug content, Drug release, Emulsification time, Visual inspection. pH, Particle size. Solid SLN – DSC, XRD, SEM, FT-IR, Refractive index, Drug Release.


Keywords: Solid lipid Nanoparticles, Microemulsion, SEM, XRD, Spray drying


Edition: Volume 8 Issue 9, September 2019,


Pages: 1274 - 1287


How to Cite this Article?

Varsha Dute, Vijay Mahajan, Amol Deshmukh, "Desloratadine Microemulsion Based Solid Lipid Nanoparticles", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART2020852, Volume 8 Issue 9, September 2019, 1274 - 1287

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