International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 121

Research Paper | Anaesthesiology | India | Volume 9 Issue 1, January 2020


To Compare the Efficacy of Epidural Ropivacaine versus Bupivacaine for Postoperative Epidural Analgesia in Total Knee Replacement Surgeries: A Prospective, Randomized, Single-blinded Controlled Study

Dr B. Girish, Dr P. Krishna Prasad


Abstract: Aim: To compare the efficacy of Bupivacaine 0.125 % (Group B) versus 0.2 % Ropivacaine (Group R), in terms of pain scores, requirement of rescue analgesia, related adverse effects, and duration of postoperative hospital stay. Methods: 100 patients were randomly allocated into two groups of 50 each. Group B received 0.125 % bupivacaine epidurally. Group R received 0.2 % ropivacaine epidurally for postoperative pain relief. All patients were monitored for postoperative pain by the visual analog scale (VAS), requirement of rescue analgesia, hemodynamic parameters and adverse effects. Results: VAS pain scores were comparable in Group B, and Group R. requirement of rescue analgesia were comparable in Group R and Group B. Adverse effects such as hypotension and delayed motor block was higher in Group B when compared to group R. Conclusion: Ropivacaine 0.2 % and bupivacaine 0.125 % were equally efficient in terms of VAS pain scores, rescue analgesic requirement, and duration of postoperative hospital stay, but ropivacaine had a better safety profile in terms of less hypotension and lesser motor block.


Keywords: Bupivacaine, Epidural, Ropivacaine, Total knee arthroplasty


Edition: Volume 9 Issue 1, January 2020,


Pages: 1216 - 1218


How to Cite this Article?

Dr B. Girish, Dr P. Krishna Prasad, "To Compare the Efficacy of Epidural Ropivacaine versus Bupivacaine for Postoperative Epidural Analgesia in Total Knee Replacement Surgeries: A Prospective, Randomized, Single-blinded Controlled Study", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20204326, Volume 9 Issue 1, January 2020, 1216 - 1218

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