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Research Paper | Medical Surgical | India | Volume 9 Issue 1, January 2020
To Compare and Evaluate the Efficacy of Esmolol and Labetalol in Attenuating Pressor Response to Laryngoscopy & Tracheal Intubation during General Anesthesia
Dr. T. S. Vinil Kumar, Dr. Kiran Kumar Gera, Dr. T. Surya Sree
Abstract: BACKGROUND: Laryngoscopy and endotracheal intubation are associated with increased sympathomimetic response. Aim: To compare and evaluate the efficiency of Esmolol and Labetalol in attenuating the haemodynamic response to Direct laryngoscopy and endotracheal intubation. MATERIALS & METHODS: It is a Prospective, randomised, double-blind study in 50 patients of ASA grade I or II aged between 2060 years of either sex who were scheduled for elective surgeries under general anaesthesia and divided into two groups (each group containing 25 patients). Group L (Labetalol): patients received injection Labetalol, 0.25 mg/kg IV bolus diluted to 10 ml with 0.9 % saline. Group E (Esmolol): patients received injection Esmolol 0.5 mg/kg IV bolus diluted to 10 ml with 0.9 % saline. All the selected patients are subjected to the same anaesthesia technique. HR, SBP, DBP and MAP were recorded before intubation, and then during intubation 0 minute, 1 min, 3 min, 5 min of intubation. RESULTS AND CONCLUSION: In lower doses, Labetalol provides better protection than Esmolol in attenuating the sympathomimetic response to laryngoscopy and intubation
Keywords: Esmolol, Labetalol, Pressor response, General anaesthesia
Edition: Volume 9 Issue 1, January 2020,
Pages: 712 - 714
How to Cite this Article?
Dr. T. S. Vinil Kumar, Dr. Kiran Kumar Gera, Dr. T. Surya Sree, "To Compare and Evaluate the Efficacy of Esmolol and Labetalol in Attenuating Pressor Response to Laryngoscopy & Tracheal Intubation during General Anesthesia", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20204113, Volume 9 Issue 1, January 2020, 712 - 714
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