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Research Paper | Biochemistry | India | Volume 9 Issue 1, January 2020
Serum Prolactin, Thyroid Stimulating Hormone and Thyroid Hormones (FT3, FT4) Concentrations in Female Patients with Infertility: An Institutional Study
Dr. Minakshi Kumari  | Dr. Prof. Bela Rose Ekka | Dr. Prof. Santosh Kumar
Abstract: Background: The prevalence of infertility is estimated between 12-14 %. Hormonal disorders of female reproductive system are comprised of a number of problems resulting from aberrant dysfunction of hypothalamic- pituitary-ovarian axis. Materials and Methods: The study was conducted on 50 women (age group 2140 years) in Biochemistry Department of RIMS, Ranchi between March 2017- March 2018. Hormonal profile were done by enhanced chemiluminescent microparticle immunoassay method on ABOTT ARCHITECT i1000SR IMMUNOASSAY analyzer.50 fertile woman with similar age were enrolled as the controls. Results: There was a positive correlation between serum TSH and prolactin levels in the infertile subjects. Hyperprolactinemia was depicted in 57 % of the infertile women while it was 7 % in the control group. The infertile women with hypothyroidism had significantly higher prolactin levels when compared to the controls. Conclusion: Hyperprolactinemia with thyroid dysfunction may be a major contributory hormonal factor in female infertility patients and estimation of prolactin, FT3, FT4, and TSH should be included in the workup for patients with female infertility.
Keywords: Prolactin, thyroid profile, infertility
Edition: Volume 9 Issue 1, January 2020,
Pages: 915 - 917
How to Cite this Article?
Dr. Minakshi Kumari, Dr. Prof. Bela Rose Ekka, Dr. Prof. Santosh Kumar, "Serum Prolactin, Thyroid Stimulating Hormone and Thyroid Hormones (FT3, FT4) Concentrations in Female Patients with Infertility: An Institutional Study", International Journal of Science and Research (IJSR), Volume 9 Issue 1, January 2020, pp. 915-917, https://www.ijsr.net/get_abstract.php?paper_id=ART20204041
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