International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064

Downloads: 111

Research Paper | Biology | India | Volume 8 Issue 12, December 2019

Effects of Ascorbic Acid and Alpha-Tocopherol on Superoxide Dismutase in Spinal Cord Injured Rats

Sheik Abdullah, Asirvatham Alwin Robert, Sultan Al Mubarak

Aim: The purpose of this study was to determine the effects of ascorbic acid and alpha-tocopherol on superoxide dismutase (SOD) in spinal cord injured rats. Methods: A total of 90 male Sprague-Dawley rats (180200 g) were used for this study. Sixty of them were subjected to spinal cord injury (SCI) and given different doses of ascorbic acid and alpha-tocopherol as treatment for 12 weeks (84 days). The remaining 30 rats were used as a control (without SCI, untreated), sham group (laminectomy only) and disease control (SCI, saline). The animals bodyweight (daily), and SOD were examined at the end of the study. Results: Evidently, at the end of the study, the level of SOD decline in rats after the injury. However, compared to the disease control, the treated rats (Groups 4, 5, 6, 7, 8 and 9) described progressive enhancements in the SOD by the end of the study. Conclusion: The findings of the study demonstrated that the administration of alpha-tocopherol and ascorbic acid increased the SOD level after SCI.

Keywords: Superoxide Dismutase, spinal cord injury, ascorbic acid, alpha-tocopherol

Edition: Volume 8 Issue 12, December 2019

Pages: 1648 - 1651

Share this Article

How to Cite this Article?

Sheik Abdullah, Asirvatham Alwin Robert, Sultan Al Mubarak, "Effects of Ascorbic Acid and Alpha-Tocopherol on Superoxide Dismutase in Spinal Cord Injured Rats", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20203767, Volume 8 Issue 12, December 2019, 1648 - 1651

Enter Your Email Address


Similar Articles with Keyword 'ascorbic acid'

Downloads: 118

Research Paper, Biology, Sudan, Volume 3 Issue 10, October 2014

Pages: 1268 - 1272

Antioxidant Activity, Total Phenolic, Flavonoid and Tannin Contents of Callus and Seeds Extracts of Fenugreek (Trigonella foenum-graecum L.)

Ammar M. A. Ali, Mawahib E. M. ElNour

Share this Article

Downloads: 147

Research Paper, Biology, India, Volume 6 Issue 1, January 2017

Pages: 679 - 682

Effect of Organic fertilizers on the Growth and Biochemical Characteristics of Okra (Abelmoschus esculentus (L.) Moench)

N. Tensingh Baliah, S. Lega Priyatharsini, C. Priya

Share this Article

Similar Articles with Keyword 'cord'

Downloads: 0

Research Paper, Biology, Philippines, Volume 10 Issue 8, August 2021

Pages: 857 - 862

Exploring Students' Mental Constructs on Evolution towards Proposed Pedagogical Interventions

Ma. Lourdes G. Narca, Dennis G. Caballes

Share this Article

Downloads: 66

Research Paper, Biology, India, Volume 9 Issue 10, October 2020

Pages: 1538 - 1538

Host Association of the Pest Intercta in Relation to Season

Dr Sanjay Sharad

Share this Article

Similar Articles with Keyword 'injury'

Downloads: 124

Research Paper, Biology, India, Volume 4 Issue 10, October 2015

Pages: 1775 - 1779

Development of Tomato Sauce Fortified with Bael and its Sensory and Chemical Evaluation

Pingale Sangeeta Avinash, Dighe Nilesh Madhav

Share this Article

Downloads: 127

Research Paper, Biology, India, Volume 5 Issue 10, October 2016

Pages: 693 - 699

A Study of Histopathogical Examination of Alcohol Induced Hepato-Toxicity in Albino Rats and Protective Effect of Cuminum cyminum

Manash Jyoti Baruah, Prasanta Kr. Baruah, Mridul Kr. Borthakur

Share this Article

Similar Articles with Keyword 'ascorbic'

Downloads: 118

Research Paper, Biology, Sudan, Volume 3 Issue 10, October 2014

Pages: 1268 - 1272

Antioxidant Activity, Total Phenolic, Flavonoid and Tannin Contents of Callus and Seeds Extracts of Fenugreek (Trigonella foenum-graecum L.)

Ammar M. A. Ali, Mawahib E. M. ElNour

Share this Article

Downloads: 147

Research Paper, Biology, India, Volume 6 Issue 1, January 2017

Pages: 679 - 682

Effect of Organic fertilizers on the Growth and Biochemical Characteristics of Okra (Abelmoschus esculentus (L.) Moench)

N. Tensingh Baliah, S. Lega Priyatharsini, C. Priya

Share this Article

Similar Articles with Keyword 'acid'

Downloads: 93

Research Paper, Biology, India, Volume 3 Issue 5, May 2014

Pages: 1582 - 1585

Protein Based on its Sequence or Structure to an Existing Protein Family

Manish Kumar, Ajay Prakash

Share this Article

Downloads: 97

Research Paper, Biology, India, Volume 5 Issue 8, August 2016

Pages: 2013 - 2017

Comparative Study of Lipid Alterations in Flight Muscles of Leucopholis lepidophora and Oryctes rhinoceros

S. B. More

Share this Article
Top