International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Open Access | Double Blind Reviewed

ISSN: 2319-7064


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Research Paper | Pathology | India | Volume 8 Issue 8, August 2019


Metastasis to Cerebellopontine Angle: A Case Report

Dr Subhashree Subhasmita Dash | Dr Soudamini Mahapatra | Dr Asaranti Kar


Abstract: Introduction: Cerebellopontine angle tumours accounts for 5-10 % of intracranial tumours. Most CPA tumours are benign, with 85 % being vestibular schwanomma, meningiomas, epidermoid cyst. Primary malignancies or metastasis to CPA are rare accounting for less than 2 % of neoplasm in CPA. Most common metastasis is from breast, lungs, nasopharynx, melanoma. Case report: A 35yr old female presented with headache for 1yr, diplopia, deviation of right angle of mouth. MRI finding was suggestive of tuberculoma. Patient took ATT for 1 month, but didnt show any improvement. Excision of tumour was done via right fronto temporal craniotomy. Operative D/D- trigeminal schwanomma, temporal glioma, meningioma was made. Tissue was sent for histopathology study. Histopathology findings sheets of malignant epithelial cells with high N: C ratio, hyperchromasia, with prominent nucleoli, mitosis- 10/10hpf. Focal areas of glial tissue and necrosis seen. Provisional diagnosis of squamous cell carcinoma / GBM made. Immunohistochemistry (panCK, GFAP, Ki67, HMB-45) done. panCK diffusely positive in tumour cells, Ki67 index -40 %, GFAP, HMB 45 negative in tumour cells. So final diagnosis of metastastic squamous cell carcinoma to CPangle made. Conclusion: Therefore it is highly advisable to do intraoperative squash cytology or frozen section biopsy for early detection and proper patient management.


Keywords: CP angle tumour, squamous cell carcinoma, IHC study


Edition: Volume 8 Issue 8, August 2019,


Pages: 983 - 985


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How to Cite this Article?

Dr Subhashree Subhasmita Dash, Dr Soudamini Mahapatra, Dr Asaranti Kar, "Metastasis to Cerebellopontine Angle: A Case Report", International Journal of Science and Research (IJSR), Volume 8 Issue 8, August 2019, pp. 983-985, https://www.ijsr.net/get_abstract.php?paper_id=ART2020277

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