In Vitro and In Vivo Anti-Diabetic Activity of a Nearly Threatened Woody Tree Species Pterospermum Xylocarpum
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064



Research Paper | Pharmaceutical Science | India | Volume 8 Issue 11, November 2019

In Vitro and In Vivo Anti-Diabetic Activity of a Nearly Threatened Woody Tree Species Pterospermum Xylocarpum

Hassanain Hataf Jaber, K. Rajyalakshmi, M. Kishore Babu, A. Krishna Satya

In the present study Nearly Threatened Woody Tree Species Pterospermum Xylocarpum was selected for the screening of crude extracts [Hexane, Chloroform, Methanol and Aqueous (Water) extracts]for their anti-diabetic activity both in vitro and in vivo. In vitro anti-diabetic activity was done by both Alpha-Amylase inhibition assay and by Glucose uptake in Yeast Cells assay.The in-vitro analysis reveals that the Methanol extract inhibits the amylase enzyme along with the standard drug. In Vivostudies Male Sprague Dawley (150 180gms) rats were used. The animals were maintained under standard environmental conditions and were fed with standard pellet diet and water ad libitum. The experimental protocol was approved by the Institutional animal ethics committee. CPCSEA guidelines were adhered during the maintenance and experiment. Four extracts [Hexane, Chloroform, Methanol and Aqueous (Water) ] have been tested for the acute hypoglycaemic activity and there was a significant change in the methanol extract administered rat models.

Keywords: Anti-diabetic activity, in-vitro, in- vivo studies, Methanol extract

Edition: Volume 8 Issue 11, November 2019

Pages: 328 - 331

Share this Article

How to Cite this Article?

Hassanain Hataf Jaber, K. Rajyalakshmi, M. Kishore Babu, A. Krishna Satya, "In Vitro and In Vivo Anti-Diabetic Activity of a Nearly Threatened Woody Tree Species Pterospermum Xylocarpum", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20202235, Volume 8 Issue 11, November 2019, 328 - 331

94 PDF Views | 72 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Anti-diabetic activity'

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 11, November 2019

Pages: 328 - 331

In Vitro and In Vivo Anti-Diabetic Activity of a Nearly Threatened Woody Tree Species Pterospermum Xylocarpum

Hassanain Hataf Jaber, K. Rajyalakshmi, M. Kishore Babu, A. Krishna Satya

Share this Article

Review Papers, Pharmaceutical Science, India, Volume 8 Issue 8, August 2019

Pages: 149 - 154

A Review on Phytochemical and Pharmacological Study of Cucumis Dipsaceus Ehrenb. (Fruit)

Gagandeep Kaur, Dr. Suman Lata

Share this Article

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 8, August 2019

Pages: 76 - 80

Antidiabetic Activity of Methanolic Fruit Extracts of Prunus Armeniaca Linn in Streptozotocin- Induced Diabetic Rats

Deepak Shrivastav, Gagandeep Kaur, Dr. Suman Lata

Share this Article

Similar Articles with Keyword 'in-vitro'

Research Paper, Pharmaceutical Science, India, Volume 6 Issue 11, November 2017

Pages: 1616 - 1625

Formulation & Evaluation of Fast Dissolving Oral Thin Film of Ropinirole HCl

Dipak P. Savant

Share this Article

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 9, September 2019

Pages: 1527 - 1533

A Study on Formulation and Evaluation of Oral Dispersible Tablets - Propranolol HCL

D. Radhika

Share this Article

Research Paper, Pharmaceutical Science, India, Volume 6 Issue 6, June 2017

Pages: 984 - 990

Characterization and Anti-Tubercular Evaluation of Mannich base Substituted Imidazole Derivatives

Karthika.S, Girija.K

Share this Article

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 9, September 2019

Pages: 1744 - 1746

Scientific Study & Antioxidant Activity of Mature Fruit Kernels of the Plant Monestera Deliciosa Liebm

Sumit Kumar, Rita Saini, S. M. Patil

Share this Article

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 6, June 2019

Pages: 1367 - 1371

Formulation Development and In-Vitro Evaluation of Microsponges Gel Loaded with Anti Fungal Drug

Kandula Swarna, Thummala Uday Kumar

Share this Article

Similar Articles with Keyword 'Methanol extract'

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 11, November 2019

Pages: 328 - 331

In Vitro and In Vivo Anti-Diabetic Activity of a Nearly Threatened Woody Tree Species Pterospermum Xylocarpum

Hassanain Hataf Jaber, K. Rajyalakshmi, M. Kishore Babu, A. Krishna Satya

Share this Article

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 6, June 2019

Pages: 1637 - 1639

Evaluation of in vitro Anti-inflammatory Activity, Total Phenolic and Flavonoid Content of Methanol Extract of Leaves of Acmella paniculata

Ngurzampuii Sailo, Sharubam Victoria, Longjam Shantabi

Share this Article
Top