International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 206 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Pharmaceutical Science | India | Volume 8 Issue 8, August 2019


Antidiabetic Activity of Methanolic Fruit Extracts of Prunus Armeniaca Linn in Streptozotocin- Induced Diabetic Rats

Deepak Shrivastav, Gagandeep Kaur, Dr. Suman Lata


Abstract: To characterize and screening of diabetes preventive effect of methanolic extract of Prunus armeniaca Linn after exposure to streptozotocin. Methanolic extract of Prunus armeniaca Linn was prepared using soxhlet apparatus and was characterized using ultraviolet spectroscopy, infra-red spectroscopy, nuclear magnetic resonance spectroscopy and mass spectroscopy. Diabetes preventive activity of methanolic extract was evaluated by giving extract to healthy Wistar rats for 18 days followed by administering streptozotocin on 19th day by intra peritoneal route along with oral administration of extract at selected doses for additional 72 hours. Glycaemic parameters were evaluated to check the glycaemic controlling effect of extracts at selected doses. In dose dependent manner methanolic extract of Prunus armeniaca Linn results in statistically significant reduction in fasting plasma glucose, glycated haemoglobin and urinary glucose levels. Dose dependent glucose lowering effect was also observed in Oral Glucose Tolerance Test. Methanolic extract of Prunus armeniaca Linn offers significant protection against streptozotocin induced diabetes.


Keywords: Anti-diabetic activity, Methanolic extract, Prunus armeniaca, Streptozotocin


Edition: Volume 8 Issue 8, August 2019,


Pages: 76 - 80


How to Cite this Article?

Deepak Shrivastav, Gagandeep Kaur, Dr. Suman Lata, "Antidiabetic Activity of Methanolic Fruit Extracts of Prunus Armeniaca Linn in Streptozotocin- Induced Diabetic Rats", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART2020124, Volume 8 Issue 8, August 2019, 76 - 80

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Methanolic extract'

Downloads: 115

Research Paper, Pharmaceutical Science, India, Volume 6 Issue 5, May 2017

Pages: 1064 - 1066

Formulation and Evaluation of Herbal Gel Containing Methanolic Extract of Annonasquamosa Leaves

Mayur Mokashi, Manjusha Dole

Share this Article

Downloads: 181

Research Paper, Pharmaceutical Science, India, Volume 8 Issue 5, May 2019

Pages: 1636 - 1639

Evaluation of Antioxidant Activity of Pomegranate Peels Phytosome

Shital Pande, Ashwin Deshmukh

Share this Article

Similar Articles with Keyword 'Antidiabetic'

Downloads: 115

Research Paper, Pharmaceutical Science, India, Volume 7 Issue 9, September 2018

Pages: 369 - 373

Antidiabetic and Anti-Hyperlipidemic Potential of Linum usitatissimum (Linn.) Seeds in Streptozotacin Induced Diabetic Rat

M. D. Kitukale, A. V. Chandewar

Share this Article

Downloads: 139

Research Paper, Pharmaceutical Science, Sri Lanka, Volume 7 Issue 8, August 2018

Pages: 731 - 734

Alpha-Amylase Inhibition Activity of Endophytic Fungi Isolated from Leaves of Artocarpus heterophyllus

Madara Kumari, Ireshika De Silva

Share this Article

Similar Articles with Keyword 'activity'

Downloads: 1

Research Paper, Pharmaceutical Science, India, Volume 10 Issue 5, May 2021

Pages: 1301 - 1304

Anti-Depressant Activity of Ethanolic Extract of Ghompherna Globosa in Swiss Albino Mice

S K. Jareena, Dr. D. Subbareddy, P. Koteeswara Reddy, M. Vamsi Krishna, V. Nikhitha, D. Abhilasha

Share this Article

Downloads: 2

Review Papers, Pharmaceutical Science, India, Volume 10 Issue 5, May 2021

Pages: 837 - 839

Review on the Health Benefits of Green Tea

Manisha Dagar, Shrestha Sharma, Garima Soni

Share this Article

Similar Articles with Keyword 'Methanolic'

Downloads: 115

Research Paper, Pharmaceutical Science, India, Volume 6 Issue 5, May 2017

Pages: 1064 - 1066

Formulation and Evaluation of Herbal Gel Containing Methanolic Extract of Annonasquamosa Leaves

Mayur Mokashi, Manjusha Dole

Share this Article

Downloads: 115

Research Paper, Pharmaceutical Science, India, Volume 7 Issue 9, September 2018

Pages: 369 - 373

Antidiabetic and Anti-Hyperlipidemic Potential of Linum usitatissimum (Linn.) Seeds in Streptozotacin Induced Diabetic Rat

M. D. Kitukale, A. V. Chandewar

Share this Article

Similar Articles with Keyword 'extract'

Downloads: 149

Research Paper, Pharmaceutical Science, India, Volume 6 Issue 12, December 2017

Pages: 286 - 290

Stability Indicating Method Development and Validation of the Trandolapril in Human Plasma by LCMS/MS in Bulk and Tablet Dosage Form

Ganipisetty Lakshmi Aswini, D.Dachinamoorthy, J. V. L. N. Seshagiri Rao

Share this Article

Downloads: 1

Research Paper, Pharmaceutical Science, India, Volume 10 Issue 5, May 2021

Pages: 1301 - 1304

Anti-Depressant Activity of Ethanolic Extract of Ghompherna Globosa in Swiss Albino Mice

S K. Jareena, Dr. D. Subbareddy, P. Koteeswara Reddy, M. Vamsi Krishna, V. Nikhitha, D. Abhilasha

Share this Article
Top