Research Paper | Medicine Science | India | Volume 8 Issue 7, July 2019
Oleoylethanolamide-based Treatment in Obesity: A Retrospective Analysis of 100 Cases from a Single Center in the Northern Territory of India
Abhyudaya Verma, Deepika Verma, Pooja Bansal, Akhil Bansal
Background & Objectives: New therapeutic approaches with minimal or no adverse effects are needed to contain and counter the epidemic of obesity. Oleoylethanolamide is a bioactive lipid mediator shown to cause satiety, weight loss, and lipolysis in clinical studies. This retrospective analysis investigated the characteristics of patients initiated on the combination of oleoylethanolamide (200 mg), pantethine (75 mg) and valine (10 mg) treatment in routine clinical care and further assessed subsequent changes in weight, glycaemic and metabolic profile. Method: The analysis reviewed electronic records of 100 obese patients treated with the above combination between July 15, 2018 and December 15, 2018. Results: At the end of 3 months, daily intake of the above combination reduced the mean weight (6.16 kg), waist circumference (4.77 cm), total body fat (3.14 %) and BMI (1.99 kg/m2), significantly (p < 0.01). The mean values of liver enzymes (ALT, and AST) and lipid parameters (TC, TG, LDL) also reduced significantly from baseline. The daily fullness increased in 76 % of patients and the cravings reduced in 85 % of patients. Conclusion: The above results suggest that the combination of OEA, pantethine, and valine could be effective in suppressing appetite and controlling weight in obese people.
Keywords: Obesity, Oleoylethanolamide, Pantethine, Valine, Appetite suppression
Edition: Volume 8 Issue 7, July 2019
Pages: 502 - 507
How to Cite this Article?
Abhyudaya Verma, Deepika Verma, Pooja Bansal, Akhil Bansal, "Oleoylethanolamide-based Treatment in Obesity: A Retrospective Analysis of 100 Cases from a Single Center in the Northern Territory of India", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20199227, Volume 8 Issue 7, July 2019, 502 - 507
51 PDF Views | 35 PDF Downloads
Video Lecture of Above Article is Not Available Yet
You be the First to Request! Press the Button below!
Similar Articles with Keyword 'Obesity'
Study of Serum Ferritin as a Component of Metabolic Syndrome
Raghavendra B M, Bharath M S, Veeranna Gowda K M, Mohammed Farooq Ahmed, Yashavanth HS
A Clinical Study of Cholelithiasis in Rural Population
Dr. Murali Mohan R, Dr. Murali Mohan R
Systemic Inflammations in Non Obese and Obese Uncontrolled Asthma
Harun Iskandar, Umar Said, Nur Ahmad Tabri
Prevalence of Metabolic Syndrome in Young Adults
Adam FMS, Diatri MC, Adam JMF, Seweng A, Tai ES
Study of Insulin Secretory Response after Oral Glucose Load in Hypertensive Subjects
Anuradha K., Dr. Ranjana Mathur, Dr. Sadhna Sood, Rohitash K