Immunomodulatory Activity of Gentiana Macrophylla Pall on C57bl/6 Mice
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064

Research Paper | Pharmacology and Toxicology | Mangolia | Volume 8 Issue 6, June 2019

Immunomodulatory Activity of Gentiana Macrophylla Pall on C57bl/6 Mice

Yondonperenlei R, Sugarmaa B, Munkhtuya TS, Ambaga M

Background: High level of ATP and NADPH and carbohydration (CHO) to formation of reduced metabolite such as gentiopicroside, secoiridoid glycosides and triterpines, and loganicacide, gentians, is the bioactive components of the (Gentianamacrophylla) gentian species of plants. Several days after antigen exposure, antigen-specific antibodies, predominantly of the IgMisotype, are generated and released into the general circulation by B-cells and plasma cells. The method: Sheep blood was put into a sterile heparinized tube. The solution was rinsed three times with saline before centrifugation at 2000 rpm for 10 min. The supernatant was abandoned and the Sheep red blood cells (SRBC) were prepared. 0.2 ml 10 % SRBC immunized was lateral tail vien injection into each mice (N.K.Jerne and A.A.Nordin., 1963). Result: A significant decrease (P<0.05) in the hemagglutination (antibody titre) was observed in the Gentianamacrophylla (GM) treated group (37, 8 %) when compared with the control group (56 %) Table 1. Conclusion: From the protonation compounds generate polyphenol compound with rich hydroxyl and alkaloid. These compounds prevent to lipid peroxidation or antioxidation and membrane protection and immunomodulation and protection of immune system.

Keywords: immunomodulation, Gentianamacrophylla pall, hemagglutination, antibody

Edition: Volume 8 Issue 6, June 2019

Pages: 2140 - 2143

Share this Article

How to Cite this Article?

Yondonperenlei R, Sugarmaa B, Munkhtuya TS, Ambaga M, "Immunomodulatory Activity of Gentiana Macrophylla Pall on C57bl/6 Mice", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20198842, Volume 8 Issue 6, June 2019, 2140 - 2143

92 PDF Views | 66 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'antibody'

Research Paper, Pharmacology and Toxicology, Mangolia, Volume 8 Issue 6, June 2019

Pages: 2140 - 2143

Immunomodulatory Activity of Gentiana Macrophylla Pall on C57bl/6 Mice

Yondonperenlei R, Sugarmaa B, Munkhtuya TS, Ambaga M

Share this Article

Research Paper, Pharmacology and Toxicology, India, Volume 9 Issue 1, January 2020

Pages: 125 - 133

Evaluation of Immunomodulatory Activity of Spirulinaiin Experimental Animals

Shaikh M. S, Nimbalkar V. V.

Share this Article
Top