Downloads: 173
Research Paper | Medical Microbiology | Saudi Arabia | Volume 8 Issue 6, June 2019
Phenotypical Detection of Extended Spectrum Beta-Lactamases Producing Escherichia coli, from Clinical Isolates in Riyadh Region, Al-Kharj City, Kingdom of Saudi Arabia
Eltayib Siddig Mohammed Saad, Adam Dawoud Abakar, Bakri Yousif Mohammed Nour, Hisham N. Altayeb, Makah Abdulmanan Badwi Ali
Background and objective: the aim of the present study was to identify the phenotypical detection of extended spectrum beta-lactamases, (ESBL) Phenomenon among Escherichia coli isolated from clinical samples in King Khalid Hospital and Price Sultan Center, Alkharj City, Riyadh Region, Kingdom of Saudi Arabia. Materials and Method: A total of 174 isolates of Escherichia coli were isolated by standard microbiological method, and identified by BD Phoenix system ( Becton Dickinson, USA), full automated microbiological machine confirmed by API 20 E ( BioMrieux, Marcy LEtoile, France). the antimicrobial susceptibility pattern of the isolates was determined by BD Phoenix system confirmed by E. test ( Epsilometer test), (Oxioid, UK) according to CLSI guideline (2008). The Extended spectrum beta- lactamases (ESBL) producing Escherichia coli were screened by BD Phoenix system confirmed by double disk diffusion method. p- value < 0.05 was counted as statistically significant. Result: more than forty two percent was found to be positive for ESBL producers and 57.5 % as non-ESBL producers, urine samples were the most frequent in this study, males were more prevalent to ESBL producers than females, high resistant of ESBL producers was observed among different family of antibiotics including, pipracillin (76.3 %), ampicillin (76.3 %), tetracycline (62.7 %), ceftriaxone (60.0 %), cefuroxime (55.0 %), trimethoprime / sulphamexazole (54.8 %), azitronam (54.1 %) and amoxicillin / Clavulanic acid (53.6 %). Meropenes, imipenem, amikacin and tigycyline were the most active against ESBL producers. Conclusion: The prevalence of ESBL producers in this study was high compared with others studies performed in Saudi Arabia, so it requires sound infection control measures, antimicrobial management and measures to detect and control their spread should be considered.
Keywords: Escherichia coli, Antibiotics resistance, ESBLs detection, Clinical isolates
Edition: Volume 8 Issue 6, June 2019
Pages: 228 - 233
How to Cite this Article?
Eltayib Siddig Mohammed Saad, Adam Dawoud Abakar, Bakri Yousif Mohammed Nour, Hisham N. Altayeb, Makah Abdulmanan Badwi Ali, "Phenotypical Detection of Extended Spectrum Beta-Lactamases Producing Escherichia coli, from Clinical Isolates in Riyadh Region, Al-Kharj City, Kingdom of Saudi Arabia", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20198426, Volume 8 Issue 6, June 2019, 228 - 233
Similar Articles with Keyword 'Escherichia coli'
Downloads: 38
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 976 - 978Detection of Pyogenic Infections among Clinical Samples Received in Department of Microbiology in Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh: A Retrospective Analysis
Nikita Mishra, Shilpi Srivastava, Namita Srivastava
Downloads: 105
Research Paper, Medical Microbiology, India, Volume 6 Issue 4, April 2017
Pages: 1986 - 1987Paediatric UTI: Recent Trends of Aetiology and Sensitivity: A Tertiary Care Hospital Study
Purba Mukherjee
Similar Articles with Keyword 'Escherichia'
Downloads: 38
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 976 - 978Detection of Pyogenic Infections among Clinical Samples Received in Department of Microbiology in Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh: A Retrospective Analysis
Nikita Mishra, Shilpi Srivastava, Namita Srivastava
Downloads: 101
Research Paper, Medical Microbiology, India, Volume 9 Issue 6, June 2020
Pages: 1478 - 1480Spectrum of Pathogenic Bacteria Isolated from the Endotracheal Tube Aspirates and their Antibiotic Sensitivity Pattern in a Tertiary Care Centre Ranchi
Archana, Manoj Kumar, A. K. Sharma
Similar Articles with Keyword 'coli'
Downloads: 24
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 1536 - 1539Analysis of Biofilm Formation and its Correlation with Antibiotic Susceptibility Pattern of Uropathogens
Smita Pokharnikar, Hemangi Walke, Neeta Jangale
Downloads: 38
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 976 - 978Detection of Pyogenic Infections among Clinical Samples Received in Department of Microbiology in Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh: A Retrospective Analysis
Nikita Mishra, Shilpi Srivastava, Namita Srivastava
Similar Articles with Keyword 'Antibiotics'
Downloads: 24
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 1536 - 1539Analysis of Biofilm Formation and its Correlation with Antibiotic Susceptibility Pattern of Uropathogens
Smita Pokharnikar, Hemangi Walke, Neeta Jangale
Downloads: 50
Research Paper, Medical Microbiology, Egypt, Volume 10 Issue 3, March 2021
Pages: 1389 - 1395Synergistic Antimicrobial Effect of Egyptian Honey with Antibiotics and Its Capability to Restore MRSA Sensitive to Oxacillin
Abdul-Hafeez M. M., Hamouda .S .M, Abd El Rahman M. F.
Similar Articles with Keyword 'resistance'
Downloads: 24
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 1536 - 1539Analysis of Biofilm Formation and its Correlation with Antibiotic Susceptibility Pattern of Uropathogens
Smita Pokharnikar, Hemangi Walke, Neeta Jangale
Downloads: 40
Research Paper, Medical Microbiology, India, Volume 10 Issue 4, April 2021
Pages: 110 - 116Microbiological Trends of Candidemia and Antifungal Susceptibility Pattern: Seven Years Experience at a Multi Super - Specialty Center in Northern India
Eshani Dewan, Vandana Verma
Similar Articles with Keyword 'detection'
Downloads: 38
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 976 - 978Detection of Pyogenic Infections among Clinical Samples Received in Department of Microbiology in Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh: A Retrospective Analysis
Nikita Mishra, Shilpi Srivastava, Namita Srivastava
Downloads: 101 | Monthly Hits: ⮙1
Research Paper, Medical Microbiology, India, Volume 6 Issue 4, April 2017
Pages: 1506 - 1509Detection of Rotavirus by ELISA in Stool Samples of Hospitalised Children
Neeraj Kumar, Bharti Malhotra, M. Anjaneya Swamy, S K Mehra
Similar Articles with Keyword 'Clinical'
Downloads: 38
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 976 - 978Detection of Pyogenic Infections among Clinical Samples Received in Department of Microbiology in Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh: A Retrospective Analysis
Nikita Mishra, Shilpi Srivastava, Namita Srivastava
Downloads: 40
Research Paper, Medical Microbiology, India, Volume 10 Issue 4, April 2021
Pages: 110 - 116Microbiological Trends of Candidemia and Antifungal Susceptibility Pattern: Seven Years Experience at a Multi Super - Specialty Center in Northern India
Eshani Dewan, Vandana Verma
Similar Articles with Keyword 'isolates'
Downloads: 24
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 1536 - 1539Analysis of Biofilm Formation and its Correlation with Antibiotic Susceptibility Pattern of Uropathogens
Smita Pokharnikar, Hemangi Walke, Neeta Jangale
Downloads: 38
Research Paper, Medical Microbiology, India, Volume 10 Issue 2, February 2021
Pages: 976 - 978Detection of Pyogenic Infections among Clinical Samples Received in Department of Microbiology in Integral Institute of Medical Sciences and Research, Lucknow, Uttar Pradesh: A Retrospective Analysis
Nikita Mishra, Shilpi Srivastava, Namita Srivastava