International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064



Downloads: 126

Research Paper | Medical Surgical | India | Volume 8 Issue 4, April 2019


Efficacy of Single Application of Doxycycline Hyclate in Treatment of Recurrent Aphthousstomatitis

Dr. Asif Mahajan [4] | Dr. Waseem Ahmad Shah | Dr. Abdul Qayoom


Abstract: Aim: The aim of the present study is to evaluate the efficacy of topical application of single dose of doxycycline hyclate 100mg tablet as a new therapeutic regimen in the treatment of minor RAU for pain reduction. Methods: The patients diagnosed with minor recurrent aphthous ulcers fulfilling the inclusion and exclusion criteria were enrolled. The study was conducted in the Department of ENT, H & NS, SKIMS-MC, Srinagar (J & K) India from January 2017 to January 2018 after approval by institutional ethical committee. This study included a total of 50 patients which were divided into two groups each of 25 patients. Group I: 25 patients receiving doxycycline hyclate 100 mg tablets (Doxt 100). Group II: 25 patients receiving placebo tablet. Results: The data indicated a significant reduction in pain in group A (i. e. , faster reduction in pain) compared with group B. On the third day, pain score was 3.80 in the study group and 5.65 in the control group [Table 1] with P value of 0.079 and it was found highly significant on the fifth day with a P value of


Keywords: Doxycycline hyclate, recurrent apthous ulcer RAU, VAS Visual Analogue Scale


Edition: Volume 8 Issue 4, April 2019,


Pages: 902 - 906


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How to Cite this Article?

Dr. Asif Mahajan, Dr. Waseem Ahmad Shah, Dr. Abdul Qayoom, "Efficacy of Single Application of Doxycycline Hyclate in Treatment of Recurrent Aphthousstomatitis", International Journal of Science and Research (IJSR), Volume 8 Issue 4, April 2019, pp. 902-906, https://www.ijsr.net/get_abstract.php?paper_id=ART20197052



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