International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 109 | Monthly Hits: ⮙1

Research Paper | Biomedical Sciences | Nigeria | Volume 8 Issue 4, April 2019


Changes in Some Reproductive Hormones Levels of Stress Induced Albino Rats Treated with Aqueous Extracts of Syzygium Aromaticum

Kebbi John Perewarebo, Brown Holyand Ebirien, Agana Samuel Bartimaeus


Abstract: The correlation between a stress exposed or a stress induced lifestyle and the etiology of reproductive challenges has come into focus, knowing that exposure to stress can lead to overproduction of reactive oxygen species which is the leading factor in the development of oxidative stress. Syzygium aromaticum extracts have been discovered to increases sperm count but excessive intake caused damages to the testicular tissues and can reduce the oxidative stress in the body. This study examined changes in some reproductive hormones of stress induced rats exposed to Syzygium aromaticum. Seven-two (72) albino rats comprising of 36 male and 36 female rats were used for the study. The Seven-two (72) were divided into six groups, consisting of three treatment groups of eight male and female albino rats. And a control group made up of four males and females. The control group was made up of the baseline group, positive control and a negative control group. The positive control received hormones analogs and feeds while the negative control did not receive any treatment apart from feeds. The treatment groups were given different dosages of 100mg/kg, 250mg/kg and 500mg/kg of Syzygium aromaticum aqueous extract orally for 28days. All the rats were exposed to stress using the Analgesymeter which induced pain except the baseline control group. After the experimental duration, all the rats were sacrificed and blood samples collected and tissues harvested. This was followed by assaying the levels of some reproductive hormones. The result revealed that the reproductive hormones of all the various extract groups of male rats exposed to Syzygium aromaticum extract were significantly higher than the baseline and negative control except for the maximum dosage at p< 0.05). Similar trend was observed for the female rat. This study brought to bear that Syzygium aromaticum extract has the tendency of increasing reproductive hormone at minimal doses, but may retard reproductive hormone at higher doses.


Keywords: oxidative, stress, reproductive, hormone, Syzygium aromaticum


Edition: Volume 8 Issue 4, April 2019,


Pages: 886 - 889


How to Cite this Article?

Kebbi John Perewarebo, Brown Holyand Ebirien, Agana Samuel Bartimaeus, "Changes in Some Reproductive Hormones Levels of Stress Induced Albino Rats Treated with Aqueous Extracts of Syzygium Aromaticum", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20196853, Volume 8 Issue 4, April 2019, 886 - 889

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'oxidative'

Downloads: 2

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 6, June 2021

Pages: 336 - 339

Comparison between Oral Simvastatin and the Addition of Mung Bean Sprout (Vigna radiata) Extract to Improve Lipid Profile and Decrease F2-isoprostane Level in Wistar Male Rats (Rattus norvegicus) with Dyslipidemia

Jessica Novia Chandra Wijaya, Anak Agung Gde Budhiarta, Ida Sri Iswari

Share this Article

Downloads: 4

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 8, August 2021

Pages: 37 - 41

Effect Oral Administration of Betel Water (Peperomia pellucida) Ethanol Extract on Lipid Profile and F2 Isoprostane Levels in Dyslipidemic Male Rats (Rattus norvegicus)

Maria Stefani Melisa, Anak Agung Gde Budhiarta, Anak Agung Gde Putra Wiraguna

Share this Article

Similar Articles with Keyword 'stress'

Downloads: 2

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 6, June 2021

Pages: 336 - 339

Comparison between Oral Simvastatin and the Addition of Mung Bean Sprout (Vigna radiata) Extract to Improve Lipid Profile and Decrease F2-isoprostane Level in Wistar Male Rats (Rattus norvegicus) with Dyslipidemia

Jessica Novia Chandra Wijaya, Anak Agung Gde Budhiarta, Ida Sri Iswari

Share this Article

Downloads: 4

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 8, August 2021

Pages: 37 - 41

Effect Oral Administration of Betel Water (Peperomia pellucida) Ethanol Extract on Lipid Profile and F2 Isoprostane Levels in Dyslipidemic Male Rats (Rattus norvegicus)

Maria Stefani Melisa, Anak Agung Gde Budhiarta, Anak Agung Gde Putra Wiraguna

Share this Article

Similar Articles with Keyword 'reproductive'

Downloads: 4

Review Papers, Biomedical Sciences, Indonesia, Volume 10 Issue 6, June 2021

Pages: 894 - 897

Potency of Secretome in Reproductive Regenerative Medicine

Megaratni Sandhi, Wimpie Pangkahila

Share this Article

Downloads: 109

Review Papers, Biomedical Sciences, India, Volume 9 Issue 7, July 2020

Pages: 1949 - 1957

Polycystic Ovary Syndrome (PCOS) Symptoms, Causes & Treatments - A Review

Nobendu Mukerjee

Share this Article

Similar Articles with Keyword 'hormone'

Downloads: 48

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 1, January 2021

Pages: 786 - 789

Intermittent Fasting with Moderate-Intensity Physical Exercise Increased Melatonin but Did Not Reduce Body Mass Index in Obese Rats

Novana O. Mantiri, Wimpie Pangkahila, Alex Pangkahila

Share this Article

Downloads: 76

Masters Thesis, Biomedical Sciences, Indonesia, Volume 10 Issue 2, February 2021

Pages: 131 - 135

Oral Administration of Ethyl Acetate Extract of Sanrego (Lunasia amara Blanco) Wood Increased the Number of Leydig Cells and Testosterone Levels in Old Male Wistar Rats (Rattus norvegicus)

Florindo Cardoso Gomes, Wimpie Pangkahila, I Gusti Made Aman

Share this Article
Top