Research Paper | Dental Science | India | Volume 8 Issue 3, March 2019
The Role of the Immunology in Periodontal Disease - Update on Current and Emergent Data
Ibrahim Fahad Alkurdi, Mohammad Jafnan Alharbi
Periodontal disease (PD) is a highly complex and multi-factorial disease. The two major factors responsible for initiation and progression of the majority of PD are the composition of the microbes in the subgingival plaque and the host immune response to these organisms. This review summarizes role of immunology and some immunological factors involved in the development and control of PD such as: bacterial complexity of PD and microbial dysbiosis, the participation of inflammatory cells in local inflammation. Despite to the fact of innate and adaptive immune activation, and resultant inflammation, our immune response fails to cure PD. Although several studies have tried to clarify some of the immune mechanisms involved in periodontal disease, role of microbial dysbiosis and immune imbalance in the pathogenesis of disease, more studies must be conducted to understand its development and progression and consequently to discover new alternatives for the prevention and treatment of this severe inflammatory disease.
Keywords: Periodontal disease, Immunology, Inflammation, Host-Pathogen interaction, Microbial dysbiosis, Chemotaxis, Complement system
Edition: Volume 8 Issue 3, March 2019
Pages: 210 - 211
How to Cite this Article?
Ibrahim Fahad Alkurdi, Mohammad Jafnan Alharbi, "The Role of the Immunology in Periodontal Disease - Update on Current and Emergent Data", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20195893, Volume 8 Issue 3, March 2019, 210 - 211
148 PDF Views | 99 PDF Downloads
Similar Articles with Keyword 'Periodontal disease'
Comparative Assessment of Oral Hygiene Practices with Socio-Demographic Factors in 15-74 Years Old Patients Reporting for Scaling in the Department of Periodontology: A Cross-Sectional Study
Prachee Hendre, Divya Agarwal, Suresh Lele, Nihal Devkar
Xerostomia ? A Review
Decisive Analysis of Smoking and Periodontal Syndrome at Selected Dental Clinics, Saudi Arabia
Dr. Alhassan Khalid Alasiari, Dr. Abrar Abdulrazaq Makhdom
Fixed Prosthodontics in Periodontally Challenged Teeth: A Case Report
Raluca Juncar, Mihai Juncar
Appraisal of Staff Perception toward Restored Endodontic Treated Teeth at Selected Dental Clinics, Saudi Arabia
Dr. Reem Abdullah Bunayyan Alkhmsan, Dr. Malak Farraj Alshammari
Similar Articles with Keyword 'Inflammation'
Role of Interleukin 1-ALPHA in GCF with Aggressive Periodontitis
Bl. Abiraamasri, Dr. Radhika
Association between Diabetes and Periodontitis
Dr. Shashirekha A, Dr. J. Jayaprakashsai
Effects of Alcohol Containing Mouthwash on Oral Tissue: A Review
Pradeep Kumar.S, Athiban Raj.J
The Effect of Chewing Gum on Periodontal Disease
Dr Alaa Omran Ali
Oral Hygiene Status and Periodontal Status (PSR) in Young Football Players from 12 to 17 Years Old in Plovdiv, Bulgaria
Atanasoski A, V Kondeva, V Stoeva, M Dimitrova, S Rimalvoska