International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 213

Research Paper | Medical Surgical | India | Volume 8 Issue 3, March 2019


Impact of Morphology of Gallstones on Histopathological Changes in Gallbladder Mucosa: A Study

M G Vashist, Manoj Soni, Manish Verma, Sunita Singh, Sahil, Shubra


Abstract: Coexistence of gallstones with cholecystitis, hyperplasia, intestinal metaplasia, and carcinoma is wellknown in literature. Gallstones may be cholesterol, pigment or mixed type. To study the impact of morphology of gallstones on histopathological changes in gallbladder mucosa was planned. The study was conducted on 50 patients of cholelithiasis, who underwent cholecystectomy. Physical characterstics of gallstones were examined and the gallbladder specimen were sent for histopathological examination. Mixed type of stones were most commonly observed in 52 % of patients and 96.1 % of patients were having multiple stones. Mural inflammation was the most common histopathological finding significantly associated with mixed type of stones. Metaplasia, dysplasia and carcinoma were found in 6 %, 2 % and 2 % of patients respectively. Present study highlights the importance of careful gross and histopathologic evaluation of gallbladders as cholelithiasis may be associated with hyperplasia, metaplasia or dysplasia; even leading to gallbladder carcinoma in certain cases.


Keywords: Cholelithiasis, gallstones, hyperplasia, metaplsia


Edition: Volume 8 Issue 3, March 2019,


Pages: 31 - 33


How to Cite this Article?

M G Vashist, Manoj Soni, Manish Verma, Sunita Singh, Sahil, Shubra, "Impact of Morphology of Gallstones on Histopathological Changes in Gallbladder Mucosa: A Study", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20195781, Volume 8 Issue 3, March 2019, 31 - 33

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Cholelithiasis'

Downloads: 22

Research Paper, Medical Surgical, India, Volume 10 Issue 4, April 2021

Pages: 281 - 283

Intra-Hepatic Perforation of Gall Bladder Causing Liver Abscess Mimicking Malignancy: A Rare Presentation

Dr. Prekshit Chhaparwal, Dr. Ashish Goyal, Dr. Brijesh Kumar Sharma, Dr. M. C. Misra

Share this Article

Downloads: 110

Review Papers, Medical Surgical, India, Volume 9 Issue 1, January 2020

Pages: 1109 - 1111

Gallstones: What the Medical Student Needs to Know

Shantanu Chandrashekhar, Sumedha Yadav, Sayali Pawar, Tanisha Shekhar

Share this Article

Similar Articles with Keyword 'gallstones'

Downloads: 110

Review Papers, Medical Surgical, India, Volume 9 Issue 1, January 2020

Pages: 1109 - 1111

Gallstones: What the Medical Student Needs to Know

Shantanu Chandrashekhar, Sumedha Yadav, Sayali Pawar, Tanisha Shekhar

Share this Article

Downloads: 112

Research Paper, Medical Surgical, Saudi Arabia, Volume 5 Issue 1, January 2016

Pages: 2019 - 2020

Ultrasound Prevalence of Gallbladder Disease in Hail, Saudi Arabia

Maram N Alawad, Abdalaziz M Almotlaq, Shaikhah H Alorf, Nouf H Alshammari, Ashjan M Almhanaa, Hanin M Aljohani, Mohammed I Elsayed

Share this Article

Similar Articles with Keyword 'hyperplasia'

Downloads: 100

Case Studies, Medical Surgical, India, Volume 4 Issue 2, February 2015

Pages: 2366 - 2368

Cutaneous Lymphoid Hyperplasia Presenting as Bilateral Post-Auricular Swellings: A Case Report

A. Q. Khan, Tanvi Tolat, Anirudha Patil

Share this Article

Downloads: 104

Case Studies, Medical Surgical, India, Volume 4 Issue 5, May 2015

Pages: 2037 - 2039

Pyogenic Granuloma of Hard Palate Masquerading as Papilloma

Viresh Arora, Bhushan Kathuria, SPS Yadav, Sharad Hernot

Share this Article
Top