Correlation between Clinical, Pathological Variables and Cancer Stem Cell Markers CD133 and CD44 in Oral Squamous Cell Carcinomas and Oral Submucosal Fibrosis
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064



Research Paper | Cancer Science | India | Volume 8 Issue 2, February 2019

Correlation between Clinical, Pathological Variables and Cancer Stem Cell Markers CD133 and CD44 in Oral Squamous Cell Carcinomas and Oral Submucosal Fibrosis

Shraddha Awasthi, Ausaf Ahmad, Anand Narain Srivastava

Oral Squamous Cell Carcinoma (OSCC) of oral Cavity is a common malignant tumor of the mouth that typically affects elderly men and women. It is more aggressive than conventional squamous cell carcinoma affecting other body regions. The cause of the condition is unknown, but genetic mutations may be involved. Factors that may influence its development include smoking and chewing of tobacco, radiation treatment for other reasons, and exposure to coal tar and arsenic. The squamous cell carcinoma may appear as slow-growing skin lesions. The lesions may ulcerate and cause scarring of the oral cavity. It may be difficult to eat, swallow food, or even to speak. The treatment of choice is a surgical excision with clear margins followed by radiation therapy or chemotherapy, as decided by the healthcare provider. In majority of the cases, the prognosis is good with appropriate treatment. This article overviews the essential points of the correlation between clicopathological variables and cancer stem cell markers CD133 and CD44 in OSCC patients and OSMF..

Keywords: : CD133, cancer stem cells, CD44, oral squamous cell carcinoma, oral sub mucosal fibrosis, clinical prognostic indicator

Edition: Volume 8 Issue 2, February 2019

Pages: 2038 - 2042

Share this Article

How to Cite this Article?

Shraddha Awasthi, Ausaf Ahmad, Anand Narain Srivastava, "Correlation between Clinical, Pathological Variables and Cancer Stem Cell Markers CD133 and CD44 in Oral Squamous Cell Carcinomas and Oral Submucosal Fibrosis", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20195608, Volume 8 Issue 2, February 2019, 2038 - 2042

87 PDF Views | 70 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'cancer stem cells'

Research Paper, Cancer Science, India, Volume 8 Issue 11, November 2019

Pages: 1002 - 1007

Immunohistochemical Evaluation of Cancer Stem Cells in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma Using Aldh1a1

Dr. Sahana Srinath, Dr Asha R Iyengar, Dr. Vijaya Mysorekar, Dr. Srinath S K

Share this Article

Research Paper, Cancer Science, India, Volume 8 Issue 2, February 2019

Pages: 2038 - 2042

Correlation between Clinical, Pathological Variables and Cancer Stem Cell Markers CD133 and CD44 in Oral Squamous Cell Carcinomas and Oral Submucosal Fibrosis

Shraddha Awasthi, Ausaf Ahmad, Anand Narain Srivastava

Share this Article

Similar Articles with Keyword 'oral squamous cell carcinoma'

Research Paper, Cancer Science, India, Volume 8 Issue 11, November 2019

Pages: 1002 - 1007

Immunohistochemical Evaluation of Cancer Stem Cells in Oral Potentially Malignant Disorders and Oral Squamous Cell Carcinoma Using Aldh1a1

Dr. Sahana Srinath, Dr Asha R Iyengar, Dr. Vijaya Mysorekar, Dr. Srinath S K

Share this Article

Research Paper, Cancer Science, India, Volume 8 Issue 2, February 2019

Pages: 2038 - 2042

Correlation between Clinical, Pathological Variables and Cancer Stem Cell Markers CD133 and CD44 in Oral Squamous Cell Carcinomas and Oral Submucosal Fibrosis

Shraddha Awasthi, Ausaf Ahmad, Anand Narain Srivastava

Share this Article
Top