International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 184

Research Paper | Oncology Science | India | Volume 8 Issue 2, February 2019


Assessment of Outcome after LLETZ in Cervical Cancer Prevention

Sumedha Gargy, Mukunda Kumar, Nishant Sinha


Abstract: The aim of the present retrospective study was to assess the recurrence rate of preinvasive disease and the newly detected invasive disease rate in a cohort of women treated with excisional methods for high-grade cervical intraepithelial neoplasia (CIN). Women were treated with large loop excision of the transformation zone (LLETZ). Surgical specimens underwent histological examination and the status of endocervical as well as ectocervical margins was recorded. Follow-up protocol included testing for HP HPV DNA at 6 months after the initial treatment following which the patients either went to normal recall if tests were normal, had annual smears or repeat LLETZ if clinically indicated. Majority [54.5 %] patients had negative TOC after LLETZ. In TOC positive patients, colposcopy was normal in 67.8 % patients, low grade and HPV were seen in 14.28 % patients each. No moderate or high grade seen. Colposcopy was normal in 75 % of patients in TOC negative group.78.9 % patients were able to go for normal recall with their GP. Only 6.2 % were advised annual smears. Among the 8 patients taken up for a biopsy, 3 turned out negative, 3 had HPV and only 2 showed CIN 1 changes. NO patient had cervical changes CIN2 or above. NONE of the patients needed a repeat LLETZ. Women having undergone excisional treatment for high-grade CIN indicate a very low risk for recurrent disease and potentially negligible risk for invasive cancer, provided that a strict and vigorous follow-up is offered after treatment.


Keywords: cervical conization, cervical intraepithelial neoplasia, CIN2-3, colposcopy, LLETZ


Edition: Volume 8 Issue 2, February 2019,


Pages: 134 - 136


How to Cite this Article?

Sumedha Gargy, Mukunda Kumar, Nishant Sinha, "Assessment of Outcome after LLETZ in Cervical Cancer Prevention", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=ART20194922, Volume 8 Issue 2, February 2019, 134 - 136

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'cervical'

Downloads: 116

Research Paper, Oncology Science, Ghana, Volume 8 Issue 1, January 2019

Pages: 1395 - 1401

Using Manchester System for the Treatment of Cervix Carcinoma for a Selected Oncology Facility in Ghana

J. Owusu-Banahene, E.O. Darko, M Abubakar, Baffour Awuah, G. Amoako

Share this Article

Downloads: 118

Research Paper, Oncology Science, India, Volume 5 Issue 12, December 2016

Pages: 1524 - 1530

The Dosimetric Comparison of Doses Distribution of Co60 Based High Dose Rate Intracavitary Brachytherapy Delivered Under General Anaesthesia v/s Conscious Sedation in Cervical Cancer Patients

Poonam Chand Bana, Narendra Kumar Rathore

Share this Article
Top